| Disease ID | Disease name | Source of annotation with GOT1 | OMIM link | Number of associated genes | genes |
|---|---|---|---|---|---|
| 614419 | ASPARTATE AMINOTRANSFERASE, SERUM LEVEL OF, QUANTITATIVE TRAIT LOCUS 1 | OMIM | link to OMIM | 1 | GOT1 |
Download the gene annotation in CSV format
| KEGG pathway | KEGG ID | KEGG IC |
|---|---|---|
| Arginine and proline metabolism | hsa00330 | 6.84 |
| Carbon metabolism | hsa01200 | 6.03 |
| Tyrosine metabolism | hsa00350 | 7.64 |
| Metabolic pathways | hsa01100 | 2.49 |
| Alanine, aspartate and glutamate metabolism | hsa00250 | 7.64 |
| Phenylalanine metabolism | hsa00360 | 8.6 |
| Biosynthesis of amino acids | hsa01230 | 6.58 |
| Cysteine and methionine metabolism | hsa00270 | 7.56 |
| Phenylalanine, tyrosine and tryptophan biosynthesis | hsa00400 | 10.45 |
| 2-Oxocarboxylic acid metabolism | hsa01210 | 8.68 |
| REACTOME pathway | REACTOME ID | REACTOME IC |
|---|---|---|
| Metabolism of carbohydrates | R-HSA-71387 | 4.93 |
| Metabolism of amino acids and derivatives | R-HSA-71291 | 5.4 |
| Methionine salvage pathway | R-HSA-1237112 | 10.4 |
| Sulfur amino acid metabolism | R-HSA-1614635 | 8.46 |
| Glucose metabolism | R-HSA-70326 | 6.77 |
| Metabolism | R-HSA-1430728 | 2.34 |
| Gluconeogenesis | R-HSA-70263 | 8.03 |
| Metabolism of polyamines | R-HSA-351202 | 9.08 |
| Amino acid synthesis and interconversion (transamination) | R-HSA-70614 | 8.89 |
| GO term | GO ID | GO IC |
|---|---|---|
| anion binding | GO:0043168 | 4.17 |
| phosphatidylserine decarboxylase activity | GO:0004609 | 9.05 |
| protein binding | GO:0005515 | 0.46 |
| L-aspartate:2-oxoglutarate aminotransferase activity | GO:0004069 | 8.64 |
| carboxylic acid binding | GO:0031406 | 4.64 |
| catalytic activity | GO:0003824 | 1.05 |
| lyase activity | GO:0016829 | 4.53 |
| carbon-carbon lyase activity | GO:0016830 | 5.81 |
| L-phenylalanine aminotransferase activity | GO:0070546 | 8.64 |
| L-phenylalanine:2-oxoglutarate aminotransferase activity | GO:0080130 | 8.64 |
| ion binding | GO:0043167 | 1.36 |
| transaminase activity | GO:0008483 | 6.74 |
| transferase activity | GO:0016740 | 1.95 |
| carboxy-lyase activity | GO:0016831 | 6.15 |
| cofactor binding | GO:0048037 | 4.16 |
| binding | GO:0005488 | 0.18 |
| L-cysteine:2-oxoglutarate aminotransferase activity | GO:0047801 | 9.74 |
| transferase activity, transferring nitrogenous groups | GO:0016769 | 6.65 |
| identical protein binding | GO:0042802 | 2.63 |
| pyridoxal phosphate binding | GO:0030170 | 5.83 |