Gene table of GP6 : glycoprotein VI platelet

Gene-disease associations table

Disease IDDisease nameSource of annotation with GP6OMIM linkNumber of associated genesgenes
PS231200BLEEDING DISORDER, PLATELET-TYPEClinVar, OMIM, HUMSAVAR link to OMIM 21NBEAL2, ANO6, GP1BA, ITGA2, GFI1B, ITGA2B, PLAU, PRKACG, P2RY12, ACTN1, TBXAS1, P2RX1, GP6, CD36, SLFN14, ITGB3, GP9, GP1BB, RASGRP2, TBXA2R, MYH9

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Annotation of the gene GP6

Associated genes in ENSEMBL
Associated proteins - SwissProt Accession ID
Associated PDB IDs
Cytogenetic Band
Tandem repeats annotation
Transcription regulation as annotated in TRRUST

It is regulated by the following TF:

Associated KEGG pathways
KEGG pathwayKEGG IDKEGG IC
Platelet activationhsa046115.66
ECM-receptor interactionhsa045126.09
Associated REACTOME pathways
REACTOME pathwayREACTOME IDREACTOME IC
Platelet Adhesion to exposed collagenR-HSA-758929.08
Platelet activation, signaling and aggregationR-HSA-760025.15
GPVI-mediated activation cascadeR-HSA-1146047.18
HemostasisR-HSA-1095823.98
Cell surface interactions at the vascular wallR-HSA-2027336.32
Associated GO terms for Molecular function
GO termGO IDGO IC
signaling receptor activityGO:00380232.49
signal transducer activityGO:00048712.28
molecular transducer activityGO:00600892.32
transmembrane signaling receptor activityGO:00048882.57
macromolecular complex bindingGO:00448772.61
receptor activityGO:00048722.32
protein bindingGO:00055150.46
protein complex bindingGO:00324033.09
collagen bindingGO:00055185.58
transmembrane receptor activityGO:00996002.53
bindingGO:00054880.18