| Disease ID | Disease name | Source of annotation with GPX1 | OMIM link | Number of associated genes | genes |
|---|---|---|---|---|---|
| 614164 | GLUTATHIONE PEROXIDASE DEFICIENCY | OMIM | link to OMIM | 1 | GPX1 |
Download the gene annotation in CSV format
| KEGG pathway | KEGG ID | KEGG IC |
|---|---|---|
| Amyotrophic lateral sclerosis (ALS) | hsa05014 | 7.01 |
| Huntington's disease | hsa05016 | 5.17 |
| Arachidonic acid metabolism | hsa00590 | 6.79 |
| Glutathione metabolism | hsa00480 | 6.96 |
| Thyroid hormone synthesis | hsa04918 | 6.56 |
| REACTOME pathway | REACTOME ID | REACTOME IC |
|---|---|---|
| Synthesis of 5-eicosatetraenoic acids | R-HSA-2142688 | 10.4 |
| Synthesis of 12-eicosatetraenoic acid derivatives | R-HSA-2142712 | 10.4 |
| Cellular responses to stress | R-HSA-2262752 | 4.56 |
| Metabolism of nucleotides | R-HSA-15869 | 6.7 |
| Purine catabolism | R-HSA-74259 | 9.66 |
| Arachidonic acid metabolism | R-HSA-2142753 | 7.34 |
| Metabolism of lipids and lipoproteins | R-HSA-556833 | 3.79 |
| Metabolism | R-HSA-1430728 | 2.34 |
| Detoxification of Reactive Oxygen Species | R-HSA-3299685 | 8.23 |
| Purine metabolism | R-HSA-73847 | 7.94 |
| Synthesis of 15-eicosatetraenoic acid derivatives | R-HSA-2142770 | 10.4 |
| GO term | GO ID | GO IC |
|---|---|---|
| antioxidant activity | GO:0016209 | 5.49 |
| protein domain specific binding | GO:0019904 | 3.32 |
| SH3 domain binding | GO:0017124 | 4.98 |
| catalytic activity | GO:0003824 | 1.05 |
| binding | GO:0005488 | 0.18 |
| protein binding | GO:0005515 | 0.46 |
| oxidoreductase activity, acting on peroxide as acceptor | GO:0016684 | 6.0 |
| peroxidase activity | GO:0004601 | 6.05 |
| glutathione peroxidase activity | GO:0004602 | 6.85 |
| oxidoreductase activity | GO:0016491 | 3.12 |