Gene table of GRHPR : glyoxylate and hydroxypyruvate reductase

Gene-disease associations table

Disease ID	Disease name	Source of annotation with GRHPR	OMIM link	Number of associated genes	genes
PS259900	HYPEROXALURIA, PRIMARY	ClinVar, OMIM	link to OMIM	3	HOGA1, AGXT, GRHPR

Associated genes in ENSEMBL

Associated proteins - SwissProt Accession ID

Associated PDB IDs

Cytogenetic Band

Tandem repeats annotation

Transcription regulation as annotated in TRRUST

Associated KEGG pathways

KEGG pathway	KEGG ID	KEGG IC
Glycine, serine and threonine metabolism	hsa00260	7.45
Pyruvate metabolism	hsa00620	7.45
Metabolic pathways	hsa01100	2.49
Glyoxylate and dicarboxylate metabolism	hsa00630	8.07

Associated REACTOME pathways

REACTOME pathway	REACTOME ID	REACTOME IC
Glyoxylate metabolism	R-HSA-389661	10.66
Metabolism	R-HSA-1430728	2.34
Metabolism of amino acids and derivatives	R-HSA-71291	5.4

Associated GO terms for Molecular function

GO term	GO ID	GO IC
NAD binding	GO:0051287	5.77
glycerate dehydrogenase activity	GO:0008465	9.74
binding	GO:0005488	0.18
glyoxylate reductase (NADP) activity	GO:0030267	9.74
ion binding	GO:0043167	1.36
heterocyclic compound binding	GO:1901363	1.06
nucleoside phosphate binding	GO:1901265	1.96
oxidoreductase activity	GO:0016491	3.12
anion binding	GO:0043168	4.17
coenzyme binding	GO:0050662	4.53
NADP binding	GO:0050661	5.93
nucleotide binding	GO:0000166	1.96
identical protein binding	GO:0042802	2.63
protein homodimerization activity	GO:0042803	3.16
small molecule binding	GO:0036094	1.89
catalytic activity	GO:0003824	1.05
cofactor binding	GO:0048037	4.16
oxidoreductase activity, acting on CH-OH group of donors	GO:0016614	4.83
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	GO:0016616	5.0
hydroxypyruvate reductase activity	GO:0016618	9.74
organic cyclic compound binding	GO:0097159	1.05
carboxylic acid binding	GO:0031406	4.64
protein binding	GO:0005515	0.46
NADPH binding	GO:0070402	7.1
protein dimerization activity	GO:0046983	2.72