Gene table of GRN : granulin precursor

Gene-disease associations table

Disease ID	Disease name	Source of annotation with GRN	OMIM link	Number of associated genes	genes
PS256730	CEROID LIPOFUSCINOSES	OMIM	link to OMIM	12	CLN8, CLN5, MFSD8, CTSD, GRN, CLN6, PPT1, DNAJC5, CLN3, CTSF, SMPD1, TPP1
607485	FRONTOTEMPORAL LOBAR DEGENERATION WITH TDP43 INCLUSIONS, GRN-RELATED	ClinVar, OMIM, HUMSAVAR	link to OMIM	1	GRN
600274	FRONTOTEMPORAL DEMENTIA	ClinVar	link to OMIM	3	GRN, MAPT, PSEN1

Associated genes in ENSEMBL

Associated proteins - SwissProt Accession ID

Associated PDB IDs

Cytogenetic Band

Tandem repeats annotation

Transcription regulation as annotated in TRRUST

Associated KEGG pathways

Associated REACTOME pathways

Associated GO terms for Molecular function

GO term	GO ID	GO IC
cytokine activity	GO:0005125	4.34
protein binding	GO:0005515	0.46
organic cyclic compound binding	GO:0097159	1.05
poly(A) RNA binding	GO:0044822	2.69
growth factor activity	GO:0008083	4.66
binding	GO:0005488	0.18
nucleic acid binding	GO:0003676	1.44
receptor binding	GO:0005102	2.43
heterocyclic compound binding	GO:1901363	1.06
RNA binding	GO:0003723	2.36