Gene table of GTF2H5 : general transcription factor IIH subunit 5

Gene-disease associations table

Disease IDDisease nameSource of annotation with GTF2H5OMIM linkNumber of associated genesgenes
PS601675TRICHOTHIODYSTROPHYClinVar, OMIM, HUMSAVAR link to OMIM 5ERCC3, MPLKIP, RNF113A, GTF2H5, ERCC2

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Annotation of the gene GTF2H5

Associated genes in ENSEMBL
Associated proteins - SwissProt Accession ID
Associated PDB IDs
Cytogenetic Band
Tandem repeats annotation
Transcription regulation as annotated in TRRUST
Associated KEGG pathways
KEGG pathwayKEGG IDKEGG IC
Basal transcription factorshsa030227.31
Nucleotide excision repairhsa034207.15
Associated REACTOME pathways
REACTOME pathwayREACTOME IDREACTOME IC
Global Genomic NER (GG-NER)R-HSA-1099707.89
Dual incision reaction in TC-NERR-HSA-1103048.12
Formation of transcription-coupled NER (TC-NER) repair complexR-HSA-1103028.12
Transcription-coupled NER (TC-NER)R-HSA-739377.49
Formation of incision complex in GG-NERR-HSA-739358.59
RNA Polymerase I Promoter EscapeR-HSA-737728.08
RNA Polymerase I Chain ElongationR-HSA-737777.18
RNA Polymerase II Promoter EscapeR-HSA-737767.52
RNA Polymerase II Transcription Pre-Initiation And Promoter OpeningR-HSA-737797.52
RNA Polymerase I Promoter ClearanceR-HSA-738546.75
DiseaseR-HSA-16436853.33
RNA Polymerase II Pre-transcription EventsR-HSA-6746957.01
Transcription of the HIV genomeR-HSA-1671726.96
Negative epigenetic regulation of rRNA expressionR-HSA-52509416.75
RNA Polymerase II Transcription Initiation And Promoter ClearanceR-HSA-760427.52
Gene ExpressionR-HSA-741602.72
Formation of the HIV-1 Early Elongation ComplexR-HSA-1671587.94
HIV InfectionR-HSA-1629065.22
Late Phase of HIV Life CycleR-HSA-1625996.02
Nucleotide Excision RepairR-HSA-738857.34
RNA Polymerase II TranscriptionR-HSA-738576.25
Infectious diseaseR-HSA-56632054.47
Epigenetic regulation of gene expressionR-HSA-2121656.46
mRNA CappingR-HSA-720868.12
RNA Polymerase I, RNA Polymerase III, and Mitochondrial TranscriptionR-HSA-5040466.16
RNA Polymerase II Transcription InitiationR-HSA-759537.52
Dual incision reaction in GG-NERR-HSA-739418.59
HIV Transcription ElongationR-HSA-1671697.59
RNA Polymerase I TranscriptionR-HSA-738646.72
HIV Transcription InitiationR-HSA-1671617.52
RNA Pol II CTD phosphorylation and interaction with CER-HSA-1671608.23
RNA Polymerase I Transcription TerminationR-HSA-738638.03
RNA Polymerase II HIV Promoter EscapeR-HSA-1671627.52
Formation of RNA Pol II elongation complex R-HSA-1123827.56
Formation of HIV elongation complex in the absence of HIV TatR-HSA-1671527.56
Formation of HIV-1 elongation complex containing HIV-1 TatR-HSA-1672007.59
RNA Pol II CTD phosphorylation and interaction with CER-HSA-770758.23
Formation of the Early Elongation ComplexR-HSA-1134187.94
NoRC negatively regulates rRNA expressionR-HSA-4274136.81
DNA RepairR-HSA-738945.8
RNA Polymerase I Transcription InitiationR-HSA-737627.43
Tat-mediated elongation of the HIV-1 transcriptR-HSA-1672467.59
HIV Life CycleR-HSA-1625875.89
RNA Polymerase II Transcription ElongationR-HSA-759557.56
Associated GO terms for Molecular function
GO termGO IDGO IC
sequence-specific DNA bindingGO:00435652.79
sequence-specific double-stranded DNA bindingGO:19908373.2
rDNA bindingGO:00001827.66
organic cyclic compound bindingGO:00971591.05
bindingGO:00054880.18
nucleic acid bindingGO:00036761.44
DNA bindingGO:00036771.92
double-stranded DNA bindingGO:00036903.09
heterocyclic compound bindingGO:19013631.06