Gene table of GUSB : glucuronidase beta

Gene-disease associations table

Disease IDDisease nameSource of annotation with GUSBOMIM linkNumber of associated genesgenes
236750HYDROPS FETALIS, NONIMMUNEClinVar link to OMIM 11MYOM1, NEU1, FZD6, DNAH14, NEB, THSD1, UBN1, CHRNA1, GALNT14, PIGC, GUSB
PS607014MUCOPOLYSACCHARIDOSESClinVar, OMIM, HUMSAVAR link to OMIM 11ARSB, SGSH, HYAL1, GALNS, IDUA, NAGLU, GNPTAB, GUSB, GLB1, IDS, HGSNAT

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Annotation of the gene GUSB

Associated genes in ENSEMBL
Associated proteins - SwissProt Accession ID
Associated PDB IDs
Cytogenetic Band
Tandem repeats annotation
Transcription regulation as annotated in TRRUST

It is regulated by the following TF:

Associated KEGG pathways
KEGG pathwayKEGG IDKEGG IC
Drug metabolism - other enzymeshsa009837.21
Metabolic pathwayshsa011002.49
Porphyrin and chlorophyll metabolismhsa008607.41
Lysosomehsa041425.78
Pentose and glucuronate interconversionshsa000407.68
Starch and sucrose metabolismhsa005006.91
Glycosaminoglycan degradationhsa005318.45
Associated REACTOME pathways
REACTOME pathwayREACTOME IDREACTOME IC
Metabolism of carbohydratesR-HSA-713874.93
MPS VII - Sly syndromeR-HSA-220629212.98
MucopolysaccharidosesR-HSA-22062819.52
Diseases of carbohydrate metabolismR-HSA-56630848.28
Heparan sulfate/heparin (HS-GAG) metabolismR-HSA-16380917.2
Diseases of metabolismR-HSA-56689146.57
Hyaluronan metabolismR-HSA-21428458.98
MetabolismR-HSA-14307282.34
Glycosaminoglycan metabolismR-HSA-16303166.04
Hyaluronan uptake and degradationR-HSA-21609169.4
HS-GAG degradationR-HSA-20240968.52
DiseaseR-HSA-16436853.33
Associated GO terms for Molecular function
GO termGO IDGO IC
hydrolase activityGO:00167871.9
hydrolase activity, hydrolyzing O-glycosyl compoundsGO:00045535.14
hydrolase activity, acting on glycosyl bondsGO:00167984.91
catalytic activityGO:00038241.05
bindingGO:00054880.18
protein bindingGO:00055150.46
beta-glucuronidase activityGO:00045668.64
receptor bindingGO:00051022.43
protein domain specific bindingGO:00199043.32