Disease ID | Disease name | Source of annotation with HCRT | OMIM link | Number of associated genes | genes |
---|---|---|---|---|---|
PS161400 | NARCOLEPSY | ClinVar, OMIM, HUMSAVAR | link to OMIM | 2 | HCRT, MOG |
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REACTOME pathway | REACTOME ID | REACTOME IC |
---|---|---|
Orexin and neuropeptides FF and QRFP bind to their respective receptors | R-HSA-389397 | 9.98 |
Signaling by GPCR | R-HSA-372790 | 2.68 |
GPCR downstream signaling | R-HSA-388396 | 3.07 |
Class A/1 (Rhodopsin-like receptors) | R-HSA-373076 | 4.69 |
Gastrin-CREB signalling pathway via PKC and MAPK | R-HSA-881907 | 4.26 |
G alpha (q) signalling events | R-HSA-416476 | 5.42 |
Peptide ligand-binding receptors | R-HSA-375276 | 5.41 |
GPCR ligand binding | R-HSA-500792 | 4.19 |
Signal Transduction | R-HSA-162582 | 1.78 |
GO term | GO ID | GO IC |
---|---|---|
hormone activity | GO:0005179 | 4.95 |
type 1 hypocretin receptor binding | GO:0031771 | 9.74 |
type 2 hypocretin receptor binding | GO:0031772 | 9.74 |
neuropeptide hormone activity | GO:0005184 | 6.34 |
hypocretin receptor binding | GO:0042324 | 9.74 |
binding | GO:0005488 | 0.18 |
protein binding | GO:0005515 | 0.46 |
neuropeptide receptor binding | GO:0071855 | 6.37 |
G-protein coupled receptor binding | GO:0001664 | 4.18 |
receptor binding | GO:0005102 | 2.43 |