Gene table of HPGD : hydroxyprostaglandin dehydrogenase 15-(NAD)

Gene-disease associations table

Disease IDDisease nameSource of annotation with HPGDOMIM linkNumber of associated genesgenes
119900DIGITAL CLUBBING, ISOLATED CONGENITALClinVar, OMIM, HUMSAVAR link to OMIM 1HPGD
PS259100HYPERTROPIC OSTEOARTHROPATHY, PRIMARYClinVar, OMIM, HUMSAVAR link to OMIM 2SLCO2A1, HPGD

Download the gene annotation in CSV format

Annotation of the gene HPGD

Associated genes in ENSEMBL
Associated proteins - SwissProt Accession ID
Associated PDB IDs
Cytogenetic Band
Tandem repeats annotation
Transcription regulation as annotated in TRRUST

It is regulated by the following TF:

Associated KEGG pathways
KEGG pathwayKEGG IDKEGG IC
Transcriptional misregulation in cancerhsa052025.21
Associated REACTOME pathways
REACTOME pathwayREACTOME IDREACTOME IC
Metabolism of lipids and lipoproteinsR-HSA-5568333.79
Arachidonic acid metabolismR-HSA-21427537.34
MetabolismR-HSA-14307282.34
Synthesis of Prostaglandins (PG) and Thromboxanes (TX)R-HSA-21621239.18
Synthesis of Lipoxins (LX)R-HSA-214270010.4
Associated GO terms for Molecular function
GO termGO IDGO IC
signaling receptor activityGO:00380232.49
NAD bindingGO:00512875.77
molecular transducer activityGO:00600892.32
icosanoid receptor activityGO:00049537.03
prostanoid receptor activityGO:00049547.44
bindingGO:00054880.18
signal transducer activityGO:00048712.28
prostaglandin E receptor activityGO:00049578.13
heterocyclic compound bindingGO:19013631.06
nucleoside phosphate bindingGO:19012651.96
oxidoreductase activityGO:00164913.12
coenzyme bindingGO:00506624.53
G-protein coupled receptor activityGO:00049302.95
nucleotide bindingGO:00001661.96
receptor activityGO:00048722.32
identical protein bindingGO:00428022.63
protein homodimerization activityGO:00428033.16
protein bindingGO:00055150.46
small molecule bindingGO:00360941.89
catalytic activityGO:00038241.05
cofactor bindingGO:00480374.16
oxidoreductase activity, acting on CH-OH group of donorsGO:00166144.83
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptorGO:00166165.0
organic cyclic compound bindingGO:00971591.05
15-hydroxyprostaglandin dehydrogenase (NAD+) activityGO:00164049.05
transmembrane signaling receptor activityGO:00048882.57
NAD+ bindingGO:00704037.17
protein dimerization activityGO:00469832.72
transmembrane receptor activityGO:00996002.53
prostaglandin receptor activityGO:00049557.54