Gene table of HSD11B2 : hydroxysteroid 11-beta dehydrogenase 2

Gene-disease associations table

Disease IDDisease nameSource of annotation with HSD11B2OMIM linkNumber of associated genesgenes
218030APPARENT MINERALOCORTICOID EXCESSClinVar, OMIM, HUMSAVAR link to OMIM 1HSD11B2

Download the gene annotation in CSV format

Annotation of the gene HSD11B2

Associated genes in ENSEMBL
Associated proteins - SwissProt Accession ID
Associated PDB IDs
Cytogenetic Band
Tandem repeats annotation
Transcription regulation as annotated in TRRUST

It is regulated by the following TF:

Associated KEGG pathways
KEGG pathwayKEGG IDKEGG IC
Aldosterone-regulated sodium reabsorptionhsa049607.41
Steroid hormone biosynthesishsa001406.93
Associated REACTOME pathways
REACTOME pathwayREACTOME IDREACTOME IC
Metabolism of lipids and lipoproteinsR-HSA-5568333.79
Glucocorticoid biosynthesisR-HSA-1940029.81
MetabolismR-HSA-14307282.34
Metabolism of steroid hormones and vitamin DR-HSA-1960717.89
Associated GO terms for Molecular function
GO termGO IDGO IC
steroid dehydrogenase activityGO:00162296.34
coenzyme bindingGO:00506624.53
steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptorGO:00337646.48
oxidoreductase activity, acting on CH-OH group of donorsGO:00166144.83
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptorGO:00166165.0
organic cyclic compound bindingGO:00971591.05
lipid bindingGO:00082893.26
nucleotide bindingGO:00001661.96
small molecule bindingGO:00360941.89
catalytic activityGO:00038241.05
cofactor bindingGO:00480374.16
bindingGO:00054880.18
11-beta-hydroxysteroid dehydrogenase [NAD(P)] activityGO:00038459.05
NAD bindingGO:00512875.77
steroid bindingGO:00054965.24
heterocyclic compound bindingGO:19013631.06
nucleoside phosphate bindingGO:19012651.96
oxidoreductase activityGO:00164913.12