| Disease ID | Disease name | Source of annotation with HTRA1 | OMIM link | Number of associated genes | genes |
|---|---|---|---|---|---|
| 616779 | CEREBRAL ARTERIOPATHY, AUTOSOMAL DOMINANT, WITH SUBCORTICAL INFARCTS AND LEUKOENCEPHALOPATHY, TYPE 2 | ClinVar, OMIM | link to OMIM | 1 | HTRA1 |
| 600142 | CEREBRAL ARTERIOPATHY, AUTOSOMAL RECESSIVE, WITH SUBCORTICAL INFARCTS AND LEUKOENCEPHALOPATHY | ClinVar, OMIM, HUMSAVAR | link to OMIM | 1 | HTRA1 |
| PS603075 | MACULAR DEGENERATION, AGE-RELATED | ClinVar, OMIM | link to OMIM | 19 | RAX2, CFB, ERCC6, TLR4, CFHR3, CFHR1, HMCN1, CFI, CFH, C3, HTRA1, ABCA4, CX3CR1, FBLN5, C2, APOE, CST3, ARMS2, C9 |
Download the gene annotation in CSV format
| GO term | GO ID | GO IC |
|---|---|---|
| hydrolase activity | GO:0016787 | 1.9 |
| endopeptidase activity | GO:0004175 | 3.63 |
| serine-type endopeptidase activity | GO:0004252 | 4.4 |
| serine hydrolase activity | GO:0017171 | 4.26 |
| growth factor binding | GO:0019838 | 4.89 |
| catalytic activity | GO:0003824 | 1.05 |
| peptidase activity, acting on L-amino acid peptides | GO:0070011 | 3.26 |
| binding | GO:0005488 | 0.18 |
| protein binding | GO:0005515 | 0.46 |
| insulin-like growth factor binding | GO:0005520 | 6.37 |
| peptidase activity | GO:0008233 | 3.23 |
| serine-type peptidase activity | GO:0008236 | 4.27 |