Gene table of HTRA2 : HtrA serine peptidase 2

Gene-disease associations table

Disease IDDisease nameSource of annotation with HTRA2OMIM linkNumber of associated genesgenes
PS168600PARKINSON DISEASEClinVar, OMIM, HUMSAVAR link to OMIM 30ATP13A2, FGF20, VPS13C, DNAJC13, ATXN2, PINK1, CHCHD2, ADH1C, UCHL1, GIGYF2, SYNJ1, PODXL, HTRA2, LRRK2, TBP, PARK2, ATXN8OS, SNCAIP, GBA, SNCA, NR4A2, PLA2G6, GLUD2, PARK7, ATXN3, MAPT, DNAJC6, EIF4G1, FBXO7, VPS35

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Annotation of the gene HTRA2

Associated genes in ENSEMBL
Associated proteins - SwissProt Accession ID
Associated PDB IDs
Cytogenetic Band
Tandem repeats annotation
Transcription regulation as annotated in TRRUST

It is regulated by the following TF:

Associated KEGG pathways
KEGG pathwayKEGG IDKEGG IC
Parkinson's diseasehsa050125.59
Associated REACTOME pathways
Associated GO terms for Molecular function
GO termGO IDGO IC
hydrolase activityGO:00167871.9
endopeptidase activityGO:00041753.63
serine-type endopeptidase activityGO:00042524.4
serine hydrolase activityGO:00171714.26
unfolded protein bindingGO:00510825.13
catalytic activityGO:00038241.05
peptidase activity, acting on L-amino acid peptidesGO:00700113.26
bindingGO:00054880.18
protein bindingGO:00055150.46
peptidase activityGO:00082333.23
serine-type peptidase activityGO:00082364.27