| Disease ID | Disease name | Source of annotation with HYAL1 | OMIM link | Number of associated genes | genes |
|---|---|---|---|---|---|
| PS607014 | MUCOPOLYSACCHARIDOSES | ClinVar, OMIM, HUMSAVAR | link to OMIM | 11 | ARSB, SGSH, HYAL1, GALNS, IDUA, NAGLU, GNPTAB, GUSB, GLB1, IDS, HGSNAT |
Download the gene annotation in CSV format
| KEGG pathway | KEGG ID | KEGG IC |
|---|---|---|
| Metabolic pathways | hsa01100 | 2.49 |
| Lysosome | hsa04142 | 5.78 |
| Glycosaminoglycan degradation | hsa00531 | 8.45 |
| REACTOME pathway | REACTOME ID | REACTOME IC |
|---|---|---|
| CS/DS degradation | R-HSA-2024101 | 9.18 |
| Metabolism of carbohydrates | R-HSA-71387 | 4.93 |
| Chondroitin sulfate/dermatan sulfate metabolism | R-HSA-1793185 | 7.34 |
| Mucopolysaccharidoses | R-HSA-2206281 | 9.52 |
| Diseases of carbohydrate metabolism | R-HSA-5663084 | 8.28 |
| MPS IX - Natowicz syndrome | R-HSA-2206280 | 12.98 |
| Diseases of metabolism | R-HSA-5668914 | 6.57 |
| Hyaluronan metabolism | R-HSA-2142845 | 8.98 |
| Metabolism | R-HSA-1430728 | 2.34 |
| Glycosaminoglycan metabolism | R-HSA-1630316 | 6.04 |
| Hyaluronan uptake and degradation | R-HSA-2160916 | 9.4 |
| Disease | R-HSA-1643685 | 3.33 |
| GO term | GO ID | GO IC |
|---|---|---|
| hydrolase activity | GO:0016787 | 1.9 |
| transferase activity, transferring glycosyl groups | GO:0016757 | 4.08 |
| molecular transducer activity | GO:0060089 | 2.32 |
| hyalurononglucosaminidase activity | GO:0004415 | 7.66 |
| transcription factor binding | GO:0008134 | 3.46 |
| virus receptor activity | GO:0001618 | 5.49 |
| hydrolase activity, acting on glycosyl bonds | GO:0016798 | 4.91 |
| hexosaminidase activity | GO:0015929 | 7.03 |
| catalytic activity | GO:0003824 | 1.05 |
| transferase activity | GO:0016740 | 1.95 |
| receptor activity | GO:0004872 | 2.32 |
| protein binding | GO:0005515 | 0.46 |
| hydrolase activity, hydrolyzing O-glycosyl compounds | GO:0004553 | 5.14 |
| transferase activity, transferring hexosyl groups | GO:0016758 | 4.43 |
| hyaluronan synthase activity | GO:0050501 | 8.35 |
| UDP-glycosyltransferase activity | GO:0008194 | 4.81 |
| binding | GO:0005488 | 0.18 |