Disease ID | Disease name | Source of annotation with IDH2 | OMIM link | Number of associated genes | genes |
---|---|---|---|---|---|
PS137800 | GLIOMA | HUMSAVAR | link to OMIM | 8 | PTEN, PPARG, ERBB2, POT1, BRCA2, IDH2, IDH1, TP53 |
PS600721 | D-2-HYDROXYGLUTARIC ACIDURIA | OMIM, HUMSAVAR | link to OMIM | 2 | IDH2, D2HGDH |
Download the gene annotation in CSV format
KEGG pathway | KEGG ID | KEGG IC |
---|---|---|
Metabolic pathways | hsa01100 | 2.49 |
Carbon metabolism | hsa01200 | 6.03 |
Glutathione metabolism | hsa00480 | 6.96 |
Citrate cycle (TCA cycle) | hsa00020 | 7.86 |
Peroxisome | hsa04146 | 6.34 |
Biosynthesis of amino acids | hsa01230 | 6.58 |
2-Oxocarboxylic acid metabolism | hsa01210 | 8.68 |
REACTOME pathway | REACTOME ID | REACTOME IC |
---|---|---|
The citric acid (TCA) cycle and respiratory electron transport | R-HSA-1428517 | 5.71 |
Pyruvate metabolism and Citric Acid (TCA) cycle | R-HSA-71406 | 7.56 |
Metabolism | R-HSA-1430728 | 2.34 |
Citric acid cycle (TCA cycle) | R-HSA-71403 | 8.73 |
GO term | GO ID | GO IC |
---|---|---|
coenzyme binding | GO:0050662 | 4.53 |
metal ion binding | GO:0046872 | 1.41 |
oxidoreductase activity, acting on CH-OH group of donors | GO:0016614 | 4.83 |
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor | GO:0016616 | 5.0 |
catalytic activity | GO:0003824 | 1.05 |
organic cyclic compound binding | GO:0097159 | 1.05 |
magnesium ion binding | GO:0000287 | 4.41 |
cation binding | GO:0043169 | 1.4 |
ion binding | GO:0043167 | 1.36 |
small molecule binding | GO:0036094 | 1.89 |
isocitrate dehydrogenase (NADP+) activity | GO:0004450 | 9.05 |
cofactor binding | GO:0048037 | 4.16 |
binding | GO:0005488 | 0.18 |
NAD binding | GO:0051287 | 5.77 |
isocitrate dehydrogenase activity | GO:0004448 | 8.13 |
nucleotide binding | GO:0000166 | 1.96 |
heterocyclic compound binding | GO:1901363 | 1.06 |
nucleoside phosphate binding | GO:1901265 | 1.96 |
oxidoreductase activity | GO:0016491 | 3.12 |