Gene table of IDS : iduronate 2-sulfatase

Gene-disease associations table

Disease IDDisease nameSource of annotation with IDSOMIM linkNumber of associated genesgenes
PS607014MUCOPOLYSACCHARIDOSESClinVar, OMIM, HUMSAVAR link to OMIM 11ARSB, SGSH, HYAL1, GALNS, IDUA, NAGLU, GNPTAB, GUSB, GLB1, IDS, HGSNAT

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Annotation of the gene IDS

Associated genes in ENSEMBL
Associated proteins - SwissProt Accession ID
Associated PDB IDs
Cytogenetic Band
Tandem repeats annotation
Transcription regulation as annotated in TRRUST
Associated KEGG pathways
KEGG pathwayKEGG IDKEGG IC
Metabolic pathwayshsa011002.49
Lysosomehsa041425.78
Glycosaminoglycan degradationhsa005318.45
Associated REACTOME pathways
REACTOME pathwayREACTOME IDREACTOME IC
MPS II - Hunter syndromeR-HSA-220629612.98
CS/DS degradationR-HSA-20241019.18
Metabolism of carbohydratesR-HSA-713874.93
Chondroitin sulfate/dermatan sulfate metabolismR-HSA-17931857.34
MucopolysaccharidosesR-HSA-22062819.52
Diseases of carbohydrate metabolismR-HSA-56630848.28
Heparan sulfate/heparin (HS-GAG) metabolismR-HSA-16380917.2
Diseases of metabolismR-HSA-56689146.57
MetabolismR-HSA-14307282.34
Glycosaminoglycan metabolismR-HSA-16303166.04
HS-GAG degradationR-HSA-20240968.52
DiseaseR-HSA-16436853.33
Associated GO terms for Molecular function
GO termGO IDGO IC
hydrolase activityGO:00167871.9
iduronate-2-sulfatase activityGO:00044239.74
cation bindingGO:00431691.4
hydrolase activity, acting on ester bondsGO:00167883.1
ion bindingGO:00431671.36
catalytic activityGO:00038241.05
bindingGO:00054880.18
sulfuric ester hydrolase activityGO:00084846.91
metal ion bindingGO:00468721.41