Disease ID | Disease name | Source of annotation with IGF1 | OMIM link | Number of associated genes | genes |
---|---|---|---|---|---|
608747 | INSULIN-LIKE GROWTH FACTOR I DEFICIENCY | OMIM | link to OMIM | 1 | IGF1 |
Download the gene annotation in CSV format
KEGG pathway | KEGG ID | KEGG IC |
---|---|---|
Melanoma | hsa05218 | 6.56 |
Focal adhesion | hsa04510 | 4.92 |
Signaling pathways regulating pluripotency of stem cells | hsa04550 | 5.6 |
Glioma | hsa05214 | 6.66 |
Prostate cancer | hsa05215 | 6.11 |
Hypertrophic cardiomyopathy (HCM) | hsa05410 | 6.21 |
FoxO signaling pathway | hsa04068 | 5.63 |
HIF-1 signaling pathway | hsa04066 | 5.9 |
Dilated cardiomyopathy | hsa05414 | 6.08 |
Aldosterone-regulated sodium reabsorption | hsa04960 | 7.41 |
mTOR signaling pathway | hsa04150 | 6.72 |
Proteoglycans in cancer | hsa05205 | 5.02 |
Pathways in cancer | hsa05200 | 3.98 |
Oocyte meiosis | hsa04114 | 5.91 |
p53 signaling pathway | hsa04115 | 6.56 |
Ovarian steroidogenesis | hsa04913 | 7.07 |
Rap1 signaling pathway | hsa04015 | 4.97 |
Ras signaling pathway | hsa04014 | 4.9 |
Inflammatory mediator regulation of TRP channels | hsa04750 | 6.07 |
Progesterone-mediated oocyte maturation | hsa04914 | 6.18 |
Transcriptional misregulation in cancer | hsa05202 | 5.21 |
AMPK signaling pathway | hsa04152 | 5.8 |
Long-term depression | hsa04730 | 6.74 |
PI3K-Akt signaling pathway | hsa04151 | 4.21 |
REACTOME pathway | REACTOME ID | REACTOME IC |
---|---|---|
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) | R-HSA-381426 | 8.59 |
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) | R-HSA-2404192 | 4.85 |
Platelet degranulation | R-HSA-114608 | 6.68 |
Platelet activation, signaling and aggregation | R-HSA-76002 | 5.15 |
Response to elevated platelet cytosolic Ca2+ | R-HSA-76005 | 6.59 |
Peptide hormone metabolism | R-HSA-2980736 | 6.61 |
IGF1R signaling cascade | R-HSA-2428924 | 4.85 |
Metabolism of proteins | R-HSA-392499 | 3.41 |
Synthesis, secretion, and deacylation of Ghrelin | R-HSA-422085 | 8.89 |
IRS-related events triggered by IGF1R | R-HSA-2428928 | 4.85 |
SHC-related events triggered by IGF1R | R-HSA-2428933 | 9.81 |
Hemostasis | R-HSA-109582 | 3.98 |
Signal Transduction | R-HSA-162582 | 1.78 |
GO term | GO ID | GO IC |
---|---|---|
hormone activity | GO:0005179 | 4.95 |
integrin binding | GO:0005178 | 5.07 |
growth factor activity | GO:0008083 | 4.66 |
organic cyclic compound binding | GO:0097159 | 1.05 |
insulin-like growth factor receptor binding | GO:0005159 | 7.03 |
insulin receptor binding | GO:0005158 | 6.27 |
lipid binding | GO:0008289 | 3.26 |
protein complex binding | GO:0032403 | 3.09 |
macromolecular complex binding | GO:0044877 | 2.61 |
binding | GO:0005488 | 0.18 |
protein binding | GO:0005515 | 0.46 |
steroid binding | GO:0005496 | 5.24 |
receptor binding | GO:0005102 | 2.43 |
cell adhesion molecule binding | GO:0050839 | 4.5 |