Gene table of IGKC : immunoglobulin kappa constant

Gene-disease associations table

Disease IDDisease nameSource of annotation with IGKCOMIM linkNumber of associated genesgenes
614102IMMUNOGLOBULIN KAPPA LIGHT CHAIN DEFICIENCYClinVar, OMIM, HUMSAVAR link to OMIM 1IGKC

Download the gene annotation in CSV format

Annotation of the gene IGKC

Associated genes in ENSEMBL
Associated proteins - SwissProt Accession ID
Associated PDB IDs
Cytogenetic Band
Tandem repeats annotation
Transcription regulation as annotated in TRRUST
Associated KEGG pathways
Associated REACTOME pathways
REACTOME pathwayREACTOME IDREACTOME IC
Role of phospholipids in phagocytosisR-HSA-20294855.47
Immune SystemR-HSA-1682562.37
Signaling by the B Cell Receptor (BCR)R-HSA-9837054.62
Adaptive Immune SystemR-HSA-12802183.19
Role of LAT2/NTAL/LAB on calcium mobilizationR-HSA-27309054.95
FCERI mediated MAPK activationR-HSA-28717964.32
FCERI mediated Ca+2 mobilizationR-HSA-28718095.45
Complement cascadeR-HSA-1666585.38
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cellR-HSA-1989334.7
Antigen activates B Cell Receptor (BCR) leading to generation of second messengersR-HSA-9836955.6
Fcgamma receptor (FCGR) dependent phagocytosisR-HSA-20294805.07
FCGR activationR-HSA-20294815.58
Regulation of actin dynamics for phagocytic cup formationR-HSA-20294825.23
Fc epsilon receptor (FCERI) signalingR-HSA-24542024.03
Innate Immune SystemR-HSA-1682493.17
Vesicle-mediated transportR-HSA-56536564.33
Scavenging of heme from plasmaR-HSA-21688805.61
Creation of C4 and C2 activatorsR-HSA-1667865.58
Classical antibody-mediated complement activationR-HSA-1736235.63
Initial triggering of complementR-HSA-1666635.51
Binding and Uptake of Ligands by Scavenger ReceptorsR-HSA-21737825.38
FCERI mediated NF-kB activationR-HSA-28718375.11
Associated GO terms for Molecular function
GO termGO IDGO IC
hydrolase activityGO:00167871.9
endopeptidase activityGO:00041753.63
serine-type endopeptidase activityGO:00042524.4
protein bindingGO:00055150.46
serine hydrolase activityGO:00171714.26
catalytic activityGO:00038241.05
peptidase activity, acting on L-amino acid peptidesGO:00700113.26
bindingGO:00054880.18
antigen bindingGO:00038235.02
immunoglobulin receptor bindingGO:00349876.48
peptidase activityGO:00082333.23
receptor bindingGO:00051022.43
serine-type peptidase activityGO:00082364.27