Gene table of IL10 : interleukin 10

Gene-disease associations table

Disease IDDisease nameSource of annotation with IL10OMIM linkNumber of associated genesgenes
614395GRAFT-VERSUS-HOST DISEASE, SUSCEPTIBILITY TOOMIM link to OMIM 1IL10
609423HUMAN IMMUNODEFICIENCY VIRUS TYPE 1, SUSCEPTIBILITY TOClinVar, OMIM link to OMIM 16HLA-C, IFNG, CCL3, CD209, IL4R, KIR3DL1, CCL2, TLR3, CCR2, CX3CR1, CCL11, CCR5, CXCL12, CCL3L1, CXCR1, IL10
180300RHEUMATOID ARTHRITISOMIM link to OMIM 9IL10, PTPN22, SLC22A4, PADI4, HLA-DRB1, NFKBIL1, IRF5, CIITA, CD244

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Annotation of the gene IL10

Associated genes in ENSEMBL
Associated proteins - SwissProt Accession ID
Associated PDB IDs
Cytogenetic Band
Tandem repeats annotation
Transcription regulation as annotated in TRRUST

It is regulated by the following TF:

Associated KEGG pathways
KEGG pathwayKEGG IDKEGG IC
Pertussishsa051336.46
Chagas disease (American trypanosomiasis)hsa051425.99
Malariahsa051447.15
Intestinal immune network for IgA productionhsa046726.79
Systemic lupus erythematosushsa053225.95
Autoimmune thyroid diseasehsa053206.62
Inflammatory bowel disease (IBD)hsa053216.43
Asthmahsa053107.34
Allograft rejectionhsa053306.91
Jak-STAT signaling pathwayhsa046305.44
T cell receptor signaling pathwayhsa046606.01
African trypanosomiasishsa051437.68
Leishmaniasishsa051406.32
Tuberculosishsa051525.17
Amoebiasishsa051465.82
Staphylococcus aureus infectionhsa051506.64
FoxO signaling pathwayhsa040685.63
Toxoplasmosishsa051455.71
Cytokine-cytokine receptor interactionhsa040604.67
Epstein-Barr virus infectionhsa051694.97
Associated REACTOME pathways
Associated GO terms for Molecular function
GO termGO IDGO IC
cytokine receptor bindingGO:00051264.14
cytokine activityGO:00051254.34
growth factor activityGO:00080834.66
growth factor receptor bindingGO:00708514.87
interleukin-10 receptor bindingGO:00051419.74
bindingGO:00054880.18
protein bindingGO:00055150.46
receptor bindingGO:00051022.43