| Disease ID | Disease name | Source of annotation with IL1B | OMIM link | Number of associated genes | genes |
|---|---|---|---|---|---|
| 608316 | CORONARY HEART DISEASE, SUSCEPTIBILITY TO, 2 | ClinVar | link to OMIM | 1 | IL1B |
| 137215 | GASTRIC CANCER, HEREDITARY DIFFUSE | OMIM | link to OMIM | 4 | IL1RN, CDH1, KRAS, IL1B |
Download the gene annotation in CSV format
| KEGG pathway | KEGG ID | KEGG IC |
|---|---|---|
| Pertussis | hsa05133 | 6.46 |
| Salmonella infection | hsa05132 | 6.29 |
| Legionellosis | hsa05134 | 6.88 |
| Graft-versus-host disease | hsa05332 | 6.84 |
| Osteoclast differentiation | hsa04380 | 5.64 |
| Type I diabetes mellitus | hsa04940 | 6.79 |
| NF-kappa B signaling pathway | hsa04064 | 6.21 |
| Cytokine-cytokine receptor interaction | hsa04060 | 4.67 |
| Chagas disease (American trypanosomiasis) | hsa05142 | 5.99 |
| African trypanosomiasis | hsa05143 | 7.68 |
| Leishmaniasis | hsa05140 | 6.32 |
| Amoebiasis | hsa05146 | 5.82 |
| Prion diseases | hsa05020 | 7.48 |
| Malaria | hsa05144 | 7.15 |
| Influenza A | hsa05164 | 5.21 |
| Apoptosis | hsa04210 | 6.23 |
| Measles | hsa05162 | 5.6 |
| Rheumatoid arthritis | hsa05323 | 6.05 |
| Inflammatory bowel disease (IBD) | hsa05321 | 6.43 |
| Toll-like receptor signaling pathway | hsa04620 | 6.0 |
| NOD-like receptor signaling pathway | hsa04621 | 6.88 |
| Cytosolic DNA-sensing pathway | hsa04623 | 6.79 |
| Inflammatory mediator regulation of TRP channels | hsa04750 | 6.07 |
| Hematopoietic cell lineage | hsa04640 | 6.18 |
| MAPK signaling pathway | hsa04010 | 4.63 |
| TNF signaling pathway | hsa04668 | 5.96 |
| Non-alcoholic fatty liver disease (NAFLD) | hsa04932 | 5.51 |
| Herpes simplex infection | hsa05168 | 5.08 |
| Tuberculosis | hsa05152 | 5.17 |
| Alzheimer's disease | hsa05010 | 5.34 |
| REACTOME pathway | REACTOME ID | REACTOME IC |
|---|---|---|
| C-type lectin receptors (CLRs) | R-HSA-5621481 | 6.06 |
| Signaling by Interleukins | R-HSA-449147 | 4.71 |
| Innate Immune System | R-HSA-168249 | 3.17 |
| CLEC7A/inflammasome pathway | R-HSA-5660668 | 10.4 |
| Interleukin-1 processing | R-HSA-448706 | 10.18 |
| Immune System | R-HSA-168256 | 2.37 |
| Cytokine Signaling in Immune system | R-HSA-1280215 | 3.74 |
| CLEC7A (Dectin-1) signaling | R-HSA-5607764 | 6.38 |
| Interleukin-1 signaling | R-HSA-446652 | 7.52 |
| GO term | GO ID | GO IC |
|---|---|---|
| cytokine receptor binding | GO:0005126 | 4.14 |
| cytokine activity | GO:0005125 | 4.34 |
| interleukin-1 receptor binding | GO:0005149 | 6.85 |
| growth factor receptor binding | GO:0070851 | 4.87 |
| binding | GO:0005488 | 0.18 |
| protein binding | GO:0005515 | 0.46 |
| receptor binding | GO:0005102 | 2.43 |
| protein domain specific binding | GO:0019904 | 3.32 |