| enzyme binding | GO:0019899 | 2.27 |
| kinase regulator activity | GO:0019207 | 4.5 |
| kinase activator activity | GO:0019209 | 5.58 |
| Rho GTPase binding | GO:0017048 | 5.36 |
| small GTPase binding | GO:0031267 | 4.13 |
| GTPase binding | GO:0051020 | 4.05 |
| macromolecular complex binding | GO:0044877 | 2.61 |
| binding | GO:0005488 | 0.18 |
| enzyme inhibitor activity | GO:0004857 | 3.78 |
| molecular function regulator | GO:0098772 | 2.51 |
| cation binding | GO:0043169 | 1.4 |
| kinase binding | GO:0019900 | 3.32 |
| phospholipid binding | GO:0005543 | 3.91 |
| ion binding | GO:0043167 | 1.36 |
| calcium ion binding | GO:0005509 | 3.17 |
| protein complex binding | GO:0032403 | 3.09 |
| metal ion binding | GO:0046872 | 1.41 |
| protein kinase regulator activity | GO:0019887 | 4.6 |
| enzyme regulator activity | GO:0030234 | 2.85 |
| GTPase activator activity | GO:0005096 | 4.11 |
| lipid binding | GO:0008289 | 3.26 |
| GTPase inhibitor activity | GO:0005095 | 7.1 |
| protein kinase binding | GO:0019901 | 3.44 |
| GTPase regulator activity | GO:0030695 | 4.01 |
| protein phosphatase binding | GO:0019903 | 4.93 |
| phosphatase binding | GO:0019902 | 4.63 |
| protein domain specific binding | GO:0019904 | 3.32 |
| phosphatidylinositol phosphate binding | GO:1901981 | 5.05 |
| phosphatidylinositol-3,4,5-trisphosphate binding | GO:0005547 | 6.21 |
| Ras GTPase binding | GO:0017016 | 4.2 |
| nucleoside-triphosphatase regulator activity | GO:0060589 | 3.92 |
| protein kinase activator activity | GO:0030295 | 5.68 |
| protein serine/threonine kinase activator activity | GO:0043539 | 6.91 |
| S100 protein binding | GO:0044548 | 7.17 |
| phosphatidylinositol binding | GO:0035091 | 4.47 |
| Rac GTPase binding | GO:0048365 | 6.05 |
| calmodulin binding | GO:0005516 | 4.55 |
| protein binding | GO:0005515 | 0.46 |
| enzyme activator activity | GO:0008047 | 3.56 |