Gene table of IRF4 : interferon regulatory factor 4

Gene-disease associations table

Disease IDDisease nameSource of annotation with IRF4OMIM linkNumber of associated genesgenes
PS227220SKIN/HAIR/EYE PIGMENTATION, VARIATION INClinVar, OMIM link to OMIM 12SLC45A2, KITLG, TYRP1, SLC24A4, ASIP, TPCN2, IRF4, HERC2, TYR, MC1R, SLC24A5, OCA2

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Annotation of the gene IRF4

Associated genes in ENSEMBL
Associated proteins - SwissProt Accession ID
Associated PDB IDs
Cytogenetic Band
Tandem repeats annotation
Transcription regulation as annotated in TRRUST

It is a TF of the genes:

It is regulated by the following TF:

Associated KEGG pathways
Associated REACTOME pathways
REACTOME pathwayREACTOME IDREACTOME IC
Interferon SignalingR-HSA-9135314.95
Cytokine Signaling in Immune systemR-HSA-12802153.74
Interferon gamma signalingR-HSA-8773005.67
Immune SystemR-HSA-1682562.37
Interferon alpha/beta signalingR-HSA-9097336.04
Associated GO terms for Molecular function
GO termGO IDGO IC
RNA polymerase II regulatory region DNA bindingGO:00010123.36
core promoter proximal region DNA bindingGO:00011593.82
protein-lysine N-methyltransferase activityGO:00162795.71
protein methyltransferase activityGO:00082765.33
bindingGO:00054880.18
nucleic acid bindingGO:00036761.44
DNA bindingGO:00036771.92
methyltransferase activityGO:00081684.35
heterocyclic compound bindingGO:19013631.06
sequence-specific DNA bindingGO:00435652.79
sequence-specific double-stranded DNA bindingGO:19908373.2
transferase activityGO:00167401.95
transferase activity, transferring one-carbon groupsGO:00167414.3
core promoter proximal region sequence-specific DNA bindingGO:00009873.83
double-stranded DNA bindingGO:00036903.09
transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific bindingGO:00009823.94
RNA polymerase II transcription factor activity, sequence-specific DNA bindingGO:00009813.29
S-adenosylmethionine-dependent methyltransferase activityGO:00087574.81
transcription factor bindingGO:00081343.46
regulatory region nucleic acid bindingGO:00010673.03
catalytic activityGO:00038241.05
N-methyltransferase activityGO:00081705.26
lysine N-methyltransferase activityGO:00162785.7
transcription regulatory region DNA bindingGO:00442123.03
transcription factor activity, sequence-specific DNA bindingGO:00037002.65
organic cyclic compound bindingGO:00971591.05
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific bindingGO:00012283.98
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific bindingGO:00010774.31
transcription regulatory region sequence-specific DNA bindingGO:00009763.24
RNA polymerase II regulatory region sequence-specific DNA bindingGO:00009773.37
protein bindingGO:00055150.46
regulatory region DNA bindingGO:00009753.03
RNA polymerase II core promoter proximal region sequence-specific DNA bindingGO:00009783.88
nucleic acid binding transcription factor activityGO:00010712.65