Gene table of IRF5 : interferon regulatory factor 5

Gene-disease associations table

Disease IDDisease nameSource of annotation with IRF5OMIM linkNumber of associated genesgenes
612251SYSTEMIC LUPUS ERYTHEMATOSUS, SUSCEPTIBILITY TO, 10ClinVar, OMIM link to OMIM 1IRF5
180300RHEUMATOID ARTHRITISClinVar link to OMIM 9IL10, PTPN22, SLC22A4, PADI4, HLA-DRB1, NFKBIL1, IRF5, CIITA, CD244
PS266600INFLAMMATORY BOWEL DISEASEOMIM link to OMIM 10ATG16L1, IL10RB, IRGM, IL10RA, NOD2, IRF5, IL23R, ABCB1, SLC22A5, IL6

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Annotation of the gene IRF5

Associated genes in ENSEMBL
Associated proteins - SwissProt Accession ID
Associated PDB IDs
Cytogenetic Band
Tandem repeats annotation
Transcription regulation as annotated in TRRUST

It is a TF of the genes:

It is regulated by the following TF:

Associated KEGG pathways
KEGG pathwayKEGG IDKEGG IC
Toll-like receptor signaling pathwayhsa046206.0
Associated REACTOME pathways
REACTOME pathwayREACTOME IDREACTOME IC
Interferon SignalingR-HSA-9135314.95
Cytokine Signaling in Immune systemR-HSA-12802153.74
Interferon gamma signalingR-HSA-8773005.67
Immune SystemR-HSA-1682562.37
Interferon alpha/beta signalingR-HSA-9097336.04
Associated GO terms for Molecular function
GO termGO IDGO IC
protein bindingGO:00055150.46
transcription factor activity, sequence-specific DNA bindingGO:00037002.65
organic cyclic compound bindingGO:00971591.05
regulatory region DNA bindingGO:00009753.03
regulatory region nucleic acid bindingGO:00010673.03
nucleic acid binding transcription factor activityGO:00010712.65
nucleic acid bindingGO:00036761.44
DNA bindingGO:00036771.92
heterocyclic compound bindingGO:19013631.06
bindingGO:00054880.18