Gene table of IRF6 : interferon regulatory factor 6

Gene-disease associations table

Disease IDDisease nameSource of annotation with IRF6OMIM linkNumber of associated genesgenes
119300VAN DER WOUDE SYNDROME 1ClinVar, OMIM, HUMSAVAR link to OMIM 1IRF6
PS119530OROFACIAL CLEFTOMIM, HUMSAVAR link to OMIM 6TP63, BMP4, IRF6, MSX1, NECTIN1, SUMO1
119500POPLITEAL PTERYGIUM SYNDROMEClinVar, OMIM, HUMSAVAR link to OMIM 1IRF6

Download the gene annotation in CSV format

Annotation of the gene IRF6

Associated genes in ENSEMBL
Associated proteins - SwissProt Accession ID
Associated PDB IDs
Cytogenetic Band
Tandem repeats annotation
Transcription regulation as annotated in TRRUST

It is a TF of the genes:

Associated KEGG pathways
Associated REACTOME pathways
REACTOME pathwayREACTOME IDREACTOME IC
Interferon SignalingR-HSA-9135314.95
Cytokine Signaling in Immune systemR-HSA-12802153.74
Interferon gamma signalingR-HSA-8773005.67
Immune SystemR-HSA-1682562.37
Interferon alpha/beta signalingR-HSA-9097336.04
Associated GO terms for Molecular function
GO termGO IDGO IC
nucleic acid bindingGO:00036761.44
transcription factor activity, sequence-specific DNA bindingGO:00037002.65
organic cyclic compound bindingGO:00971591.05
regulatory region DNA bindingGO:00009753.03
regulatory region nucleic acid bindingGO:00010673.03
nucleic acid binding transcription factor activityGO:00010712.65
protein bindingGO:00055150.46
DNA bindingGO:00036771.92
heterocyclic compound bindingGO:19013631.06
bindingGO:00054880.18