Gene table of IRF7 : interferon regulatory factor 7

Gene-disease associations table

Disease IDDisease nameSource of annotation with IRF7OMIM linkNumber of associated genesgenes
616345IMMUNODEFICIENCY 39ClinVar, OMIM, HUMSAVAR link to OMIM 1IRF7

Download the gene annotation in CSV format

Annotation of the gene IRF7

Associated genes in ENSEMBL
Associated proteins - SwissProt Accession ID
Associated PDB IDs
Cytogenetic Band
Tandem repeats annotation
Transcription regulation as annotated in TRRUST

It is a TF of the genes:

It is regulated by the following TF:

Associated KEGG pathways
KEGG pathwayKEGG IDKEGG IC
Toll-like receptor signaling pathwayhsa046206.0
RIG-I-like receptor signaling pathwayhsa046226.62
Cytosolic DNA-sensing pathwayhsa046236.79
Herpes simplex infectionhsa051685.08
Viral carcinogenesishsa052035.08
Influenza Ahsa051645.21
Hepatitis Chsa051605.68
Hepatitis Bhsa051615.52
Measleshsa051625.6
Associated REACTOME pathways
REACTOME pathwayREACTOME IDREACTOME IC
TRIF-mediated TLR3/TLR4 signaling R-HSA-9370616.47
Immune SystemR-HSA-1682562.37
Cytokine Signaling in Immune systemR-HSA-12802153.74
RIG-I/MDA5 mediated induction of IFN-alpha/beta pathwaysR-HSA-1689286.7
Factors involved in megakaryocyte development and platelet productionR-HSA-9832315.88
DEx/H-box helicases activate type I IFN and inflammatory cytokines production R-HSA-31349639.28
TRAF3-dependent IRF activation pathwayR-HSA-9182339.18
Toll Like Receptor 3 (TLR3) CascadeR-HSA-1681646.47
Toll-Like Receptors CascadesR-HSA-1688985.91
Interferon gamma signalingR-HSA-8773005.67
Interferon SignalingR-HSA-9135314.95
TRAF6 mediated IRF7 activationR-HSA-9335417.98
Toll Like Receptor 4 (TLR4) CascadeR-HSA-1660166.11
Toll Like Receptor 7/8 (TLR7/8) CascadeR-HSA-1681816.68
Innate Immune SystemR-HSA-1682493.17
MyD88-independent TLR3/TLR4 cascade R-HSA-1661666.47
Cytosolic sensors of pathogen-associated DNA R-HSA-18349496.94
TRAF6 mediated IRF7 activation in TLR7/8 or 9 signalingR-HSA-9751109.08
MyD88 dependent cascade initiated on endosomeR-HSA-9751556.68
Interferon alpha/beta signalingR-HSA-9097336.04
Activated TLR4 signallingR-HSA-1660546.27
Activation of IRF3/IRF7 mediated by TBK1/IKK epsilonR-HSA-9369648.81
HemostasisR-HSA-1095823.98
Toll Like Receptor 9 (TLR9) CascadeR-HSA-1681386.62
Associated GO terms for Molecular function
GO termGO IDGO IC
RNA polymerase II regulatory region DNA bindingGO:00010123.36
nucleic acid binding transcription factor activityGO:00010712.65
nucleic acid bindingGO:00036761.44
DNA bindingGO:00036771.92
heterocyclic compound bindingGO:19013631.06
sequence-specific DNA bindingGO:00435652.79
sequence-specific double-stranded DNA bindingGO:19908373.2
double-stranded DNA bindingGO:00036903.09
transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific bindingGO:00009823.94
RNA polymerase II transcription factor activity, sequence-specific DNA bindingGO:00009813.29
regulatory region nucleic acid bindingGO:00010673.03
core promoter bindingGO:00010474.71
core promoter sequence-specific DNA bindingGO:00010465.12
transcription regulatory region DNA bindingGO:00442123.03
transcription factor activity, sequence-specific DNA bindingGO:00037002.65
organic cyclic compound bindingGO:00971591.05
transcription regulatory region sequence-specific DNA bindingGO:00009763.24
RNA polymerase II regulatory region sequence-specific DNA bindingGO:00009773.37
protein bindingGO:00055150.46
regulatory region DNA bindingGO:00009753.03
RNA polymerase II core promoter sequence-specific DNA bindingGO:00009795.77
bindingGO:00054880.18