| Disease ID | Disease name | Source of annotation with IRF8 | OMIM link | Number of associated genes | genes |
|---|---|---|---|---|---|
| 614893 | IMMUNODEFICIENCY 32A | ClinVar, OMIM, HUMSAVAR | link to OMIM | 1 | IRF8 |
| 614894 | IMMUNODEFICIENCY 32B | ClinVar, OMIM, HUMSAVAR | link to OMIM | 1 | IRF8 |
Download the gene annotation in CSV format
| KEGG pathway | KEGG ID | KEGG IC |
|---|---|---|
| Pertussis | hsa05133 | 6.46 |
| REACTOME pathway | REACTOME ID | REACTOME IC |
|---|---|---|
| Interferon Signaling | R-HSA-913531 | 4.95 |
| Cytokine Signaling in Immune system | R-HSA-1280215 | 3.74 |
| Interferon gamma signaling | R-HSA-877300 | 5.67 |
| Immune System | R-HSA-168256 | 2.37 |
| Interferon alpha/beta signaling | R-HSA-909733 | 6.04 |
| GO term | GO ID | GO IC |
|---|---|---|
| protein binding | GO:0005515 | 0.46 |
| transcription factor activity, sequence-specific DNA binding | GO:0003700 | 2.65 |
| organic cyclic compound binding | GO:0097159 | 1.05 |
| regulatory region DNA binding | GO:0000975 | 3.03 |
| regulatory region nucleic acid binding | GO:0001067 | 3.03 |
| transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding | GO:0003705 | 5.23 |
| binding | GO:0005488 | 0.18 |
| nucleic acid binding | GO:0003676 | 1.44 |
| DNA binding | GO:0003677 | 1.92 |
| heterocyclic compound binding | GO:1901363 | 1.06 |
| RNA polymerase II transcription factor activity, sequence-specific DNA binding | GO:0000981 | 3.29 |
| nucleic acid binding transcription factor activity | GO:0001071 | 2.65 |