| Disease ID | Disease name | Source of annotation with ITGA2 | OMIM link | Number of associated genes | genes |
|---|---|---|---|---|---|
| PS231200 | BLEEDING DISORDER, PLATELET-TYPE | OMIM | link to OMIM | 21 | NBEAL2, ANO6, GP1BA, ITGA2, GFI1B, ITGA2B, PLAU, PRKACG, P2RY12, ACTN1, TBXAS1, P2RX1, GP6, CD36, SLFN14, ITGB3, GP9, GP1BB, RASGRP2, TBXA2R, MYH9 |
Download the gene annotation in CSV format
| KEGG pathway | KEGG ID | KEGG IC |
|---|---|---|
| Platelet activation | hsa04611 | 5.66 |
| Focal adhesion | hsa04510 | 4.92 |
| Proteoglycans in cancer | hsa05205 | 5.02 |
| Pathways in cancer | hsa05200 | 3.98 |
| ECM-receptor interaction | hsa04512 | 6.09 |
| Small cell lung cancer | hsa05222 | 6.17 |
| Hematopoietic cell lineage | hsa04640 | 6.18 |
| Hypertrophic cardiomyopathy (HCM) | hsa05410 | 6.21 |
| Phagosome | hsa04145 | 5.27 |
| Arrhythmogenic right ventricular cardiomyopathy (ARVC) | hsa05412 | 6.32 |
| Regulation of actin cytoskeleton | hsa04810 | 4.9 |
| Dilated cardiomyopathy | hsa05414 | 6.08 |
| PI3K-Akt signaling pathway | hsa04151 | 4.21 |
| REACTOME pathway | REACTOME ID | REACTOME IC |
|---|---|---|
| Integrin cell surface interactions | R-HSA-216083 | 6.57 |
| L1CAM interactions | R-HSA-373760 | 6.19 |
| Laminin interactions | R-HSA-3000157 | 8.08 |
| ECM proteoglycans | R-HSA-3000178 | 6.75 |
| Platelet Adhesion to exposed collagen | R-HSA-75892 | 9.08 |
| Extracellular matrix organization | R-HSA-1474244 | 4.91 |
| CHL1 interactions | R-HSA-447041 | 9.81 |
| Syndecan interactions | R-HSA-3000170 | 8.23 |
| Non-integrin membrane-ECM interactions | R-HSA-3000171 | 7.1 |
| Axon guidance | R-HSA-422475 | 3.93 |
| Hemostasis | R-HSA-109582 | 3.98 |
| Developmental Biology | R-HSA-1266738 | 3.48 |
| GO term | GO ID | GO IC |
|---|---|---|
| protein binding involved in cell-matrix adhesion | GO:0098634 | 7.95 |
| signaling receptor activity | GO:0038023 | 2.49 |
| protein binding involved in cell adhesion | GO:0098631 | 6.91 |
| extracellular matrix binding | GO:0050840 | 5.79 |
| collagen binding involved in cell-matrix adhesion | GO:0098639 | 8.13 |
| collagen receptor activity | GO:0038064 | 8.35 |
| molecular transducer activity | GO:0060089 | 2.32 |
| macromolecular complex binding | GO:0044877 | 2.61 |
| binding | GO:0005488 | 0.18 |
| signal transducer activity | GO:0004871 | 2.28 |
| cation binding | GO:0043169 | 1.4 |
| ion binding | GO:0043167 | 1.36 |
| protein complex binding | GO:0032403 | 3.09 |
| metal ion binding | GO:0046872 | 1.41 |
| integrin binding | GO:0005178 | 5.07 |
| cell adhesion molecule binding | GO:0050839 | 4.5 |
| protein dimerization activity | GO:0046983 | 2.72 |
| laminin binding | GO:0043236 | 6.34 |
| protein heterodimerization activity | GO:0046982 | 3.64 |
| virus receptor activity | GO:0001618 | 5.49 |
| transmembrane signaling receptor activity | GO:0004888 | 2.57 |
| protein binding | GO:0005515 | 0.46 |
| receptor binding | GO:0005102 | 2.43 |
| collagen binding | GO:0005518 | 5.58 |
| transmembrane receptor activity | GO:0099600 | 2.53 |
| receptor activity | GO:0004872 | 2.32 |