Disease ID | Disease name | Source of annotation with LEPR | OMIM link | Number of associated genes | genes |
---|---|---|---|---|---|
614963 | LEPTIN RECEPTOR DEFICIENCY | ClinVar, OMIM | link to OMIM | 1 | LEPR |
Download the gene annotation in CSV format
KEGG pathway | KEGG ID | KEGG IC |
---|---|---|
Neuroactive ligand-receptor interaction | hsa04080 | 4.58 |
Jak-STAT signaling pathway | hsa04630 | 5.44 |
Cytokine-cytokine receptor interaction | hsa04060 | 4.67 |
AMPK signaling pathway | hsa04152 | 5.8 |
Non-alcoholic fatty liver disease (NAFLD) | hsa04932 | 5.51 |
Adipocytokine signaling pathway | hsa04920 | 6.6 |
REACTOME pathway | REACTOME ID | REACTOME IC |
---|---|---|
Signaling by Leptin | R-HSA-2586552 | 5.1 |
Signal Transduction | R-HSA-162582 | 1.78 |
GO term | GO ID | GO IC |
---|---|---|
binding | GO:0005488 | 0.18 |
signaling receptor activity | GO:0038023 | 2.49 |
protein binding | GO:0005515 | 0.46 |
leptin receptor activity | GO:0038021 | 9.74 |
molecular transducer activity | GO:0060089 | 2.32 |
transmembrane signaling receptor activity | GO:0004888 | 2.57 |
receptor activity | GO:0004872 | 2.32 |
signal transducer activity | GO:0004871 | 2.28 |
transmembrane receptor activity | GO:0099600 | 2.53 |
identical protein binding | GO:0042802 | 2.63 |
cytokine receptor activity | GO:0004896 | 5.24 |