Gene table of LIPC : lipase C, hepatic type

Gene-disease associations table

Disease IDDisease nameSource of annotation with LIPCOMIM linkNumber of associated genesgenes
612797HIGH DENSITY LIPOPROTEIN CHOLESTEROL LEVEL QUANTITATIVE TRAIT LOCUS 12ClinVar, OMIM link to OMIM 1LIPC
125853DIABETES MELLITUS, NONINSULIN-DEPENDENTClinVar, OMIM link to OMIM 33SLC2A2, HNF4A, TCF7L2, SLC30A8, GPD2, PAX4, PTPN1, SLC2A4, ABCC8, HMGA1, LIPC, NEUROD1, CDKAL1, WFS1, PPARG, RETN, AKT2, IRS2, IL6, IRS1, GCGR, CAPN10, IGF2BP2, INSR, PDX1, MTNR1B, GCK, HNF1B, HNF1A, MAPK8IP1, ENPP1, PPP1R3A, KCNJ11
614025HEPATIC LIPASE DEFICIENCYClinVar, OMIM, HUMSAVAR link to OMIM 1LIPC

Download the gene annotation in CSV format

Annotation of the gene LIPC

Associated genes in ENSEMBL
Associated proteins - SwissProt Accession ID
Associated PDB IDs
Cytogenetic Band
Tandem repeats annotation
Transcription regulation as annotated in TRRUST

It is regulated by the following TF:

Associated KEGG pathways
KEGG pathwayKEGG IDKEGG IC
Glycerolipid metabolismhsa005616.91
Metabolic pathwayshsa011002.49
Associated REACTOME pathways
Associated GO terms for Molecular function
GO termGO IDGO IC
sulfur compound bindingGO:19016814.32
macromolecular complex bindingGO:00448772.61
bindingGO:00054880.18
glycoprotein bindingGO:00019485.11
heparin bindingGO:00082014.68
transferase activityGO:00167401.95
transferase activity, transferring acyl groupsGO:00167464.2
acylglycerol lipase activityGO:00473727.44
hydrolase activityGO:00167871.9
phosphatidylcholine 1-acylhydrolase activityGO:00089707.34
lipid bindingGO:00082893.26
carboxylic ester hydrolase activityGO:00526894.81
catalytic activityGO:00038241.05
heparan sulfate proteoglycan bindingGO:00433956.85
proteoglycan bindingGO:00433946.34
hydrolase activity, acting on ester bondsGO:00167883.1
apolipoprotein bindingGO:00341856.97
low-density lipoprotein particle bindingGO:00301697.03
lipoprotein particle bindingGO:00718136.56
triglyceride lipase activityGO:00048066.74
protein-lipid complex bindingGO:00718146.56
carbohydrate derivative bindingGO:00973672.03
glycosaminoglycan bindingGO:00055394.42
protein bindingGO:00055150.46
lysophospholipase activityGO:00046226.69
phospholipase activityGO:00046205.16
lipase activityGO:00162984.96