Gene table of LRP8 : LDL receptor related protein 8

Gene-disease associations table

Disease ID	Disease name	Source of annotation with LRP8	OMIM link	Number of associated genes	genes
608446	MYOCARDIAL INFARCTION, SUSCEPTIBILITY TO	OMIM	link to OMIM	14	LTA, ACE, ITGB3, OLR1, GCLC, ESR1, GCLM, LGALS2, MIAT, LRP8, F7, PSMA6, F13A1, TNFSF4

Associated genes in ENSEMBL

Associated proteins - SwissProt Accession ID

Associated PDB IDs

Cytogenetic Band

Tandem repeats annotation

Transcription regulation as annotated in TRRUST

Associated KEGG pathways

Associated REACTOME pathways

REACTOME pathway	REACTOME ID	REACTOME IC
Retinoid metabolism and transport	R-HSA-975634	7.59
Visual phototransduction	R-HSA-2187338	6.44
Platelet homeostasis	R-HSA-418346	6.68
Platelet sensitization by LDL	R-HSA-432142	8.89
Hemostasis	R-HSA-109582	3.98
Signal Transduction	R-HSA-162582	1.78

Associated GO terms for Molecular function

GO term	GO ID	GO IC
reelin receptor activity	GO:0038025	9.05
cargo receptor activity	GO:0038024	5.53
very-low-density lipoprotein particle receptor activity	GO:0030229	8.35
lipoprotein particle receptor activity	GO:0030228	6.97
molecular transducer activity	GO:0060089	2.32
kinesin binding	GO:0019894	6.24
macromolecular complex binding	GO:0044877	2.61
binding	GO:0005488	0.18
signal transducer activity	GO:0004871	2.28
signaling receptor activity	GO:0038023	2.49
cation binding	GO:0043169	1.4
ion binding	GO:0043167	1.36
calcium ion binding	GO:0005509	3.17
metal ion binding	GO:0046872	1.41
high-density lipoprotein particle binding	GO:0008035	7.66
apolipoprotein binding	GO:0034185	6.97
lipoprotein particle binding	GO:0071813	6.56
protein-lipid complex binding	GO:0071814	6.56
cytoskeletal protein binding	GO:0008092	3.02
low-density lipoprotein receptor activity	GO:0005041	7.17
transmembrane signaling receptor activity	GO:0004888	2.57
protein binding	GO:0005515	0.46
transmembrane receptor activity	GO:0099600	2.53
receptor activity	GO:0004872	2.32