Gene table of LSS : lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)

Gene-disease associations table

Disease IDDisease nameSource of annotation with LSSOMIM linkNumber of associated genesgenes
PS116200CATARACTClinVar, OMIM, HUMSAVAR link to OMIM 33GCNT2, CRYGD, VIM, CRYBB2, PITX3, UNC45B, BFSP1, GJA8, MAF, AGK, EPHA2, CRYBB3, MIP, CRYBA2, CRYGS, CRYBB1, FYCO1, SIPA1L3, CRYAB, GJA3, BFSP2, TDRD7, HSF4, CHMP4B, CRYAA, LIM2, WFS1, CRYBA4, LSS, CRYBA1, CRYGB, CRYGC, NHS

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Annotation of the gene LSS

Associated genes in ENSEMBL
Associated proteins - SwissProt Accession ID
Associated PDB IDs
Cytogenetic Band
Tandem repeats annotation
Transcription regulation as annotated in TRRUST

It is regulated by the following TF:

Associated KEGG pathways
KEGG pathwayKEGG IDKEGG IC
Steroid biosynthesishsa001008.45
Metabolic pathwayshsa011002.49
Associated REACTOME pathways
REACTOME pathwayREACTOME IDREACTOME IC
Metabolism of lipids and lipoproteinsR-HSA-5568333.79
Regulation of cholesterol biosynthesis by SREBP (SREBF)R-HSA-16558297.23
Cholesterol biosynthesisR-HSA-1912738.46
MetabolismR-HSA-14307282.34
Activation of gene expression by SREBF (SREBP)R-HSA-24261687.62
Associated GO terms for Molecular function
GO termGO IDGO IC
intramolecular transferase activityGO:00168666.44
catalytic activityGO:00038241.05
oxidosqualene cyclase activityGO:00315599.74
isomerase activityGO:00168534.62
lanosterol synthase activityGO:00002509.74