Disease ID | Disease name | Source of annotation with LTA | OMIM link | Number of associated genes | genes |
---|---|---|---|---|---|
608446 | MYOCARDIAL INFARCTION, SUSCEPTIBILITY TO | OMIM | link to OMIM | 14 | LTA, ACE, ITGB3, OLR1, GCLC, ESR1, GCLM, LGALS2, MIAT, LRP8, F7, PSMA6, F13A1, TNFSF4 |
610988 | LEPROSY, SUSCEPTIBILITY TO, 4 | OMIM | link to OMIM | 1 | LTA |
607507 | PSORIATIC ARTHRITIS, SUSCEPTIBILITY TO | OMIM | link to OMIM | 2 | NOD2, LTA |
Download the gene annotation in CSV format
KEGG pathway | KEGG ID | KEGG IC |
---|---|---|
Herpes simplex infection | hsa05168 | 5.08 |
TNF signaling pathway | hsa04668 | 5.96 |
Type I diabetes mellitus | hsa04940 | 6.79 |
NF-kappa B signaling pathway | hsa04064 | 6.21 |
HTLV-I infection | hsa05166 | 4.59 |
Cytokine-cytokine receptor interaction | hsa04060 | 4.67 |
REACTOME pathway | REACTOME ID | REACTOME IC |
---|---|---|
Cytokine Signaling in Immune system | R-HSA-1280215 | 3.74 |
TNFs bind their physiological receptors | R-HSA-5669034 | 8.34 |
TNFR2 non-canonical NF-kB pathway | R-HSA-5668541 | 6.4 |
Immune System | R-HSA-168256 | 2.37 |
TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway | R-HSA-5676594 | 8.89 |
GO term | GO ID | GO IC |
---|---|---|
cytokine receptor binding | GO:0005126 | 4.14 |
tumor necrosis factor receptor superfamily binding | GO:0032813 | 5.89 |
tumor necrosis factor receptor binding | GO:0005164 | 6.3 |
cytokine activity | GO:0005125 | 4.34 |
binding | GO:0005488 | 0.18 |
protein binding | GO:0005515 | 0.46 |
receptor binding | GO:0005102 | 2.43 |