Gene table of LTA : lymphotoxin alpha

Gene-disease associations table

Disease IDDisease nameSource of annotation with LTAOMIM linkNumber of associated genesgenes
608446MYOCARDIAL INFARCTION, SUSCEPTIBILITY TOOMIM link to OMIM 14LTA, ACE, ITGB3, OLR1, GCLC, ESR1, GCLM, LGALS2, MIAT, LRP8, F7, PSMA6, F13A1, TNFSF4
610988LEPROSY, SUSCEPTIBILITY TO, 4OMIM link to OMIM 1LTA
607507PSORIATIC ARTHRITIS, SUSCEPTIBILITY TOOMIM link to OMIM 2NOD2, LTA

Download the gene annotation in CSV format

Annotation of the gene LTA

Associated genes in ENSEMBL
Associated proteins - SwissProt Accession ID
Associated PDB IDs
Cytogenetic Band
Tandem repeats annotation
Transcription regulation as annotated in TRRUST

It is regulated by the following TF:

Associated KEGG pathways
KEGG pathwayKEGG IDKEGG IC
Herpes simplex infectionhsa051685.08
TNF signaling pathwayhsa046685.96
Type I diabetes mellitushsa049406.79
NF-kappa B signaling pathwayhsa040646.21
HTLV-I infectionhsa051664.59
Cytokine-cytokine receptor interactionhsa040604.67
Associated REACTOME pathways
REACTOME pathwayREACTOME IDREACTOME IC
Cytokine Signaling in Immune systemR-HSA-12802153.74
TNFs bind their physiological receptorsR-HSA-56690348.34
TNFR2 non-canonical NF-kB pathwayR-HSA-56685416.4
Immune SystemR-HSA-1682562.37
TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathwayR-HSA-56765948.89
Associated GO terms for Molecular function
GO termGO IDGO IC
cytokine receptor bindingGO:00051264.14
tumor necrosis factor receptor superfamily bindingGO:00328135.89
tumor necrosis factor receptor bindingGO:00051646.3
cytokine activityGO:00051254.34
bindingGO:00054880.18
protein bindingGO:00055150.46
receptor bindingGO:00051022.43