| Disease ID | Disease name | Source of annotation with MALT1 | OMIM link | Number of associated genes | genes |
|---|---|---|---|---|---|
| 615468 | IMMUNODEFICIENCY 12 | ClinVar, OMIM, HUMSAVAR | link to OMIM | 1 | MALT1 |
Download the gene annotation in CSV format
| KEGG pathway | KEGG ID | KEGG IC |
|---|---|---|
| T cell receptor signaling pathway | hsa04660 | 6.01 |
| NF-kappa B signaling pathway | hsa04064 | 6.21 |
| B cell receptor signaling pathway | hsa04662 | 6.52 |
| Tuberculosis | hsa05152 | 5.17 |
| REACTOME pathway | REACTOME ID | REACTOME IC |
|---|---|---|
| C-type lectin receptors (CLRs) | R-HSA-5621481 | 6.06 |
| Downstream TCR signaling | R-HSA-202424 | 7.01 |
| Fc epsilon receptor (FCERI) signaling | R-HSA-2454202 | 4.03 |
| Innate Immune System | R-HSA-168249 | 3.17 |
| CLEC7A/inflammasome pathway | R-HSA-5660668 | 10.4 |
| Immune System | R-HSA-168256 | 2.37 |
| Signaling by the B Cell Receptor (BCR) | R-HSA-983705 | 4.62 |
| Adaptive Immune System | R-HSA-1280218 | 3.19 |
| CLEC7A (Dectin-1) signaling | R-HSA-5607764 | 6.38 |
| Downstream signaling events of B Cell Receptor (BCR) | R-HSA-1168372 | 5.59 |
| Activation of NF-kappaB in B cells | R-HSA-1169091 | 6.94 |
| TCR signaling | R-HSA-202403 | 6.64 |
| FCERI mediated NF-kB activation | R-HSA-2871837 | 5.11 |
| GO term | GO ID | GO IC |
|---|---|---|
| ubiquitin-like protein transferase activity | GO:0019787 | 3.69 |
| hydrolase activity | GO:0016787 | 1.9 |
| endopeptidase activity | GO:0004175 | 3.63 |
| kinase regulator activity | GO:0019207 | 4.5 |
| protein binding | GO:0005515 | 0.46 |
| enzyme regulator activity | GO:0030234 | 2.85 |
| kinase activator activity | GO:0019209 | 5.58 |
| enzyme binding | GO:0019899 | 2.27 |
| peptidase activity, acting on L-amino acid peptides | GO:0070011 | 3.26 |
| catalytic activity | GO:0003824 | 1.05 |
| transferase activity | GO:0016740 | 1.95 |
| cysteine-type endopeptidase activity | GO:0004197 | 5.28 |
| binding | GO:0005488 | 0.18 |
| signal transducer activity | GO:0004871 | 2.28 |
| protease binding | GO:0002020 | 5.08 |
| peptidase activity | GO:0008233 | 3.23 |
| molecular function regulator | GO:0098772 | 2.51 |
| ubiquitin-protein transferase activity | GO:0004842 | 3.73 |
| cysteine-type peptidase activity | GO:0008234 | 4.51 |
| protein self-association | GO:0043621 | 5.93 |
| enzyme activator activity | GO:0008047 | 3.56 |