Gene table of MCM6 : minichromosome maintenance complex component 6

Gene-disease associations table

Disease IDDisease nameSource of annotation with MCM6OMIM linkNumber of associated genesgenes
223100LACTOSE INTOLERANCE, ADULT TYPEOMIM link to OMIM 1MCM6

Download the gene annotation in CSV format

Annotation of the gene MCM6

Associated genes in ENSEMBL
Associated proteins - SwissProt Accession ID
Associated PDB IDs
Cytogenetic Band
Tandem repeats annotation
Transcription regulation as annotated in TRRUST

It is a TF of the genes:

It is regulated by the following TF:

Associated KEGG pathways
KEGG pathwayKEGG IDKEGG IC
DNA replicationhsa030307.48
Cell cyclehsa041105.68
Associated REACTOME pathways
REACTOME pathwayREACTOME IDREACTOME IC
Mitotic G1-G1/S phasesR-HSA-4532795.91
S PhaseR-HSA-692426.02
Activation of the pre-replicative complexR-HSA-689628.08
Assembly of the pre-replicative complexR-HSA-688676.92
Switching of origins to a post-replicative stateR-HSA-690526.85
Unwinding of DNAR-HSA-1769749.4
DNA ReplicationR-HSA-693066.25
Orc1 removal from chromatinR-HSA-689496.85
M/G1 TransitionR-HSA-688746.62
G2/M CheckpointsR-HSA-694816.46
Cell Cycle CheckpointsR-HSA-696205.64
G1/S TransitionR-HSA-692066.21
DNA strand elongationR-HSA-691907.94
Regulation of DNA replicationR-HSA-693046.75
DNA Replication Pre-InitiationR-HSA-690026.62
Cell Cycle, MitoticR-HSA-692784.16
Synthesis of DNAR-HSA-692396.37
Removal of licensing factors from originsR-HSA-693006.81
Cell CycleR-HSA-16401703.89
Activation of ATR in response to replication stressR-HSA-1761877.77
Associated GO terms for Molecular function
GO termGO IDGO IC
ATPase activityGO:00168873.65
ATP-dependent helicase activityGO:00080265.12
purine ribonucleoside triphosphate bindingGO:00356392.22
bindingGO:00054880.18
nucleic acid bindingGO:00036761.44
DNA bindingGO:00036771.92
DNA helicase activityGO:00036785.73
heterocyclic compound bindingGO:19013631.06
purine nucleoside bindingGO:00018832.22
nucleoside bindingGO:00018822.21
ATPase activity, coupledGO:00426233.97
nucleotide bindingGO:00001661.96
nucleoside phosphate bindingGO:19012651.96
ribonucleoside bindingGO:00325492.22
purine nucleotide bindingGO:00170762.19
single-stranded DNA bindingGO:00036975.17
identical protein bindingGO:00428022.63
hydrolase activityGO:00167871.9
ATP-dependent DNA helicase activityGO:00040036.13
nucleoside-triphosphatase activityGO:00171113.09
helicase activityGO:00043864.69
small molecule bindingGO:00360941.89
catalytic activityGO:00038241.05
DNA-dependent ATPase activityGO:00080945.31
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydridesGO:00168183.03
adenyl nucleotide bindingGO:00305542.4
carbohydrate derivative bindingGO:00973672.03
organic cyclic compound bindingGO:00971591.05
hydrolase activity, acting on acid anhydridesGO:00168173.03
pyrophosphatase activityGO:00164623.04
adenyl ribonucleotide bindingGO:00325592.41
ATP bindingGO:00055242.43
protein bindingGO:00055150.46
purine NTP-dependent helicase activityGO:00700355.12
purine ribonucleotide bindingGO:00325552.2
purine ribonucleoside bindingGO:00325502.22
ribonucleotide bindingGO:00325532.19