Disease ID | Disease name | Source of annotation with MMP1 | OMIM link | Number of associated genes | genes |
---|---|---|---|---|---|
606963 | PULMONARY DISEASE, CHRONIC OBSTRUCTIVE | OMIM | link to OMIM | 3 | SERPINA1, HMOX1, MMP1 |
610504 | PRETERM PREMATURE RUPTURE OF THE MEMBRANES | ClinVar | link to OMIM | 3 | SERPINH1, MMP1, MMP8 |
226600 | EPIDERMOLYSIS BULLOSA DYSTROPHICA, AUTOSOMAL RECESSIVE | OMIM | link to OMIM | 2 | MMP1, COL7A1 |
Download the gene annotation in CSV format
KEGG pathway | KEGG ID | KEGG IC |
---|---|---|
Rheumatoid arthritis | hsa05323 | 6.05 |
Bladder cancer | hsa05219 | 7.38 |
PPAR signaling pathway | hsa03320 | 6.56 |
Pathways in cancer | hsa05200 | 3.98 |
REACTOME pathway | REACTOME ID | REACTOME IC |
---|---|---|
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) | R-HSA-381426 | 8.59 |
Degradation of the extracellular matrix | R-HSA-1474228 | 6.11 |
Metabolism of proteins | R-HSA-392499 | 3.41 |
Cell surface interactions at the vascular wall | R-HSA-202733 | 6.32 |
Activation of Matrix Metalloproteinases | R-HSA-1592389 | 8.03 |
Extracellular matrix organization | R-HSA-1474244 | 4.91 |
Basigin interactions | R-HSA-210991 | 8.34 |
Collagen degradation | R-HSA-1442490 | 7.03 |
Hemostasis | R-HSA-109582 | 3.98 |
GO term | GO ID | GO IC |
---|---|---|
hydrolase activity | GO:0016787 | 1.9 |
endopeptidase activity | GO:0004175 | 3.63 |
metalloendopeptidase activity | GO:0004222 | 5.02 |
calcium ion binding | GO:0005509 | 3.17 |
transition metal ion binding | GO:0046914 | 2.48 |
serine hydrolase activity | GO:0017171 | 4.26 |
metal ion binding | GO:0046872 | 1.41 |
cation binding | GO:0043169 | 1.4 |
ion binding | GO:0043167 | 1.36 |
catalytic activity | GO:0003824 | 1.05 |
peptidase activity, acting on L-amino acid peptides | GO:0070011 | 3.26 |
zinc ion binding | GO:0008270 | 2.66 |
serine-type endopeptidase activity | GO:0004252 | 4.4 |
peptidase activity | GO:0008233 | 3.23 |
serine-type peptidase activity | GO:0008236 | 4.27 |
metallopeptidase activity | GO:0008237 | 4.5 |
binding | GO:0005488 | 0.18 |