Gene table of MMP3 : matrix metallopeptidase 3

Gene-disease associations table

Disease IDDisease nameSource of annotation with MMP3OMIM linkNumber of associated genesgenes
614466CORONARY HEART DISEASE, SUSCEPTIBILITY TO, 6ClinVar, OMIM link to OMIM 1MMP3

Download the gene annotation in CSV format

Annotation of the gene MMP3

Associated genes in ENSEMBL
Associated proteins - SwissProt Accession ID
Associated PDB IDs
Cytogenetic Band
Tandem repeats annotation

The gene is in the tandem Group 538, together with the genes:

Transcription regulation as annotated in TRRUST

It is regulated by the following TF:

Associated KEGG pathways
KEGG pathwayKEGG IDKEGG IC
TNF signaling pathwayhsa046685.96
Rheumatoid arthritishsa053236.05
Transcriptional misregulation in cancerhsa052025.21
Associated REACTOME pathways
REACTOME pathwayREACTOME IDREACTOME IC
Signaling by GPCRR-HSA-3727902.68
Gastrin-CREB signalling pathway via PKC and MAPKR-HSA-8819074.26
Degradation of the extracellular matrixR-HSA-14742286.11
Collagen degradationR-HSA-14424907.03
Activation of Matrix MetalloproteinasesR-HSA-15923898.03
Extracellular matrix organizationR-HSA-14742444.91
Collagen formationR-HSA-14742906.56
EGFR Transactivation by GastrinR-HSA-21793929.81
Assembly of collagen fibrils and other multimeric structuresR-HSA-20220907.2
Signal TransductionR-HSA-1625821.78
Associated GO terms for Molecular function
GO termGO IDGO IC
hydrolase activityGO:00167871.9
endopeptidase activityGO:00041753.63
metalloendopeptidase activityGO:00042225.02
transition metal ion bindingGO:00469142.48
serine hydrolase activityGO:00171714.26
metal ion bindingGO:00468721.41
zinc ion bindingGO:00082702.66
cation bindingGO:00431691.4
ion bindingGO:00431671.36
catalytic activityGO:00038241.05
peptidase activity, acting on L-amino acid peptidesGO:00700113.26
calcium ion bindingGO:00055093.17
protein bindingGO:00055150.46
serine-type endopeptidase activityGO:00042524.4
peptidase activityGO:00082333.23
serine-type peptidase activityGO:00082364.27
metallopeptidase activityGO:00082374.5
bindingGO:00054880.18