Disease ID | Disease name | Source of annotation with MMP3 | OMIM link | Number of associated genes | genes |
---|---|---|---|---|---|
614466 | CORONARY HEART DISEASE, SUSCEPTIBILITY TO, 6 | ClinVar, OMIM | link to OMIM | 1 | MMP3 |
Download the gene annotation in CSV format
KEGG pathway | KEGG ID | KEGG IC |
---|---|---|
TNF signaling pathway | hsa04668 | 5.96 |
Rheumatoid arthritis | hsa05323 | 6.05 |
Transcriptional misregulation in cancer | hsa05202 | 5.21 |
REACTOME pathway | REACTOME ID | REACTOME IC |
---|---|---|
Signaling by GPCR | R-HSA-372790 | 2.68 |
Gastrin-CREB signalling pathway via PKC and MAPK | R-HSA-881907 | 4.26 |
Degradation of the extracellular matrix | R-HSA-1474228 | 6.11 |
Collagen degradation | R-HSA-1442490 | 7.03 |
Activation of Matrix Metalloproteinases | R-HSA-1592389 | 8.03 |
Extracellular matrix organization | R-HSA-1474244 | 4.91 |
Collagen formation | R-HSA-1474290 | 6.56 |
EGFR Transactivation by Gastrin | R-HSA-2179392 | 9.81 |
Assembly of collagen fibrils and other multimeric structures | R-HSA-2022090 | 7.2 |
Signal Transduction | R-HSA-162582 | 1.78 |
GO term | GO ID | GO IC |
---|---|---|
hydrolase activity | GO:0016787 | 1.9 |
endopeptidase activity | GO:0004175 | 3.63 |
metalloendopeptidase activity | GO:0004222 | 5.02 |
transition metal ion binding | GO:0046914 | 2.48 |
serine hydrolase activity | GO:0017171 | 4.26 |
metal ion binding | GO:0046872 | 1.41 |
zinc ion binding | GO:0008270 | 2.66 |
cation binding | GO:0043169 | 1.4 |
ion binding | GO:0043167 | 1.36 |
catalytic activity | GO:0003824 | 1.05 |
peptidase activity, acting on L-amino acid peptides | GO:0070011 | 3.26 |
calcium ion binding | GO:0005509 | 3.17 |
protein binding | GO:0005515 | 0.46 |
serine-type endopeptidase activity | GO:0004252 | 4.4 |
peptidase activity | GO:0008233 | 3.23 |
serine-type peptidase activity | GO:0008236 | 4.27 |
metallopeptidase activity | GO:0008237 | 4.5 |
binding | GO:0005488 | 0.18 |