Disease ID | Disease name | Source of annotation with MS4A2 | OMIM link | Number of associated genes | genes |
---|---|---|---|---|---|
147050 | IGE RESPONSIVENESS, ATOPIC | OMIM | link to OMIM | 8 | HAVCR1, PLA2G7, MS4A2, PHF11, SELP, IL4R, SPINK5, IL21R |
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KEGG pathway | KEGG ID | KEGG IC |
---|---|---|
Fc epsilon RI signaling pathway | hsa04664 | 6.6 |
Asthma | hsa05310 | 7.34 |
REACTOME pathway | REACTOME ID | REACTOME IC |
---|---|---|
Fc epsilon receptor (FCERI) signaling | R-HSA-2454202 | 4.03 |
Immune System | R-HSA-168256 | 2.37 |
FCERI mediated MAPK activation | R-HSA-2871796 | 4.32 |
Innate Immune System | R-HSA-168249 | 3.17 |
FCERI mediated Ca+2 mobilization | R-HSA-2871809 | 5.45 |
FCERI mediated NF-kB activation | R-HSA-2871837 | 5.11 |
Role of LAT2/NTAL/LAB on calcium mobilization | R-HSA-2730905 | 4.95 |
GO term | GO ID | GO IC |
---|---|---|
IgE binding | GO:0019863 | 8.13 |
immunoglobulin binding | GO:0019865 | 6.6 |
macromolecular complex binding | GO:0044877 | 2.61 |
binding | GO:0005488 | 0.18 |
protein binding | GO:0005515 | 0.46 |
protein complex binding | GO:0032403 | 3.09 |