| Disease ID | Disease name | Source of annotation with MT-ND2 | OMIM link | Number of associated genes | genes |
|---|---|---|---|---|---|
| 535000 | LEBER OPTIC ATROPHY | HUMSAVAR | link to OMIM | 9 | MT-ND5, MT-ATP6, MT-CO3, MT-ND4, MT-ND1, MT-CYB, MT-ND6, MT-ND4L, MT-ND2 |
| 502500 | ALZHEIMER DISEASE, SUSCEPTIBILITY TO, MITOCHONDRIAL | HUMSAVAR | link to OMIM | 2 | MT-ND1, MT-ND2 |
Download the gene annotation in CSV format
| KEGG pathway | KEGG ID | KEGG IC |
|---|---|---|
| Metabolic pathways | hsa01100 | 2.49 |
| Parkinson's disease | hsa05012 | 5.59 |
| Oxidative phosphorylation | hsa00190 | 5.69 |
| REACTOME pathway | REACTOME ID | REACTOME IC |
|---|---|---|
| Metabolism | R-HSA-1430728 | 2.34 |
| Respiratory electron transport | R-HSA-611105 | 6.44 |
| Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. | R-HSA-163200 | 6.12 |
| The citric acid (TCA) cycle and respiratory electron transport | R-HSA-1428517 | 5.71 |
| GO term | GO ID | GO IC |
|---|---|---|
| ionotropic glutamate receptor binding | GO:0035255 | 6.56 |
| kinase binding | GO:0019900 | 3.32 |
| NADH dehydrogenase (ubiquinone) activity | GO:0008137 | 5.93 |
| catalytic activity | GO:0003824 | 1.05 |
| enzyme binding | GO:0019899 | 2.27 |
| glutamate receptor binding | GO:0035254 | 6.13 |
| protein kinase binding | GO:0019901 | 3.44 |
| oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor | GO:0016655 | 5.66 |
| oxidoreductase activity, acting on NAD(P)H | GO:0016651 | 5.13 |
| NADH dehydrogenase (quinone) activity | GO:0050136 | 5.93 |
| protein binding | GO:0005515 | 0.46 |
| receptor binding | GO:0005102 | 2.43 |
| oxidoreductase activity | GO:0016491 | 3.12 |
| NADH dehydrogenase activity | GO:0003954 | 5.93 |
| binding | GO:0005488 | 0.18 |