Disease ID | Disease name | Source of annotation with MT-ND2 | OMIM link | Number of associated genes | genes |
---|---|---|---|---|---|
535000 | LEBER OPTIC ATROPHY | HUMSAVAR | link to OMIM | 9 | MT-ND5, MT-ATP6, MT-CO3, MT-ND4, MT-ND1, MT-CYB, MT-ND6, MT-ND4L, MT-ND2 |
502500 | ALZHEIMER DISEASE, SUSCEPTIBILITY TO, MITOCHONDRIAL | HUMSAVAR | link to OMIM | 2 | MT-ND1, MT-ND2 |
Download the gene annotation in CSV format
KEGG pathway | KEGG ID | KEGG IC |
---|---|---|
Metabolic pathways | hsa01100 | 2.49 |
Parkinson's disease | hsa05012 | 5.59 |
Oxidative phosphorylation | hsa00190 | 5.69 |
REACTOME pathway | REACTOME ID | REACTOME IC |
---|---|---|
Metabolism | R-HSA-1430728 | 2.34 |
Respiratory electron transport | R-HSA-611105 | 6.44 |
Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. | R-HSA-163200 | 6.12 |
The citric acid (TCA) cycle and respiratory electron transport | R-HSA-1428517 | 5.71 |
GO term | GO ID | GO IC |
---|---|---|
ionotropic glutamate receptor binding | GO:0035255 | 6.56 |
kinase binding | GO:0019900 | 3.32 |
NADH dehydrogenase (ubiquinone) activity | GO:0008137 | 5.93 |
catalytic activity | GO:0003824 | 1.05 |
enzyme binding | GO:0019899 | 2.27 |
glutamate receptor binding | GO:0035254 | 6.13 |
protein kinase binding | GO:0019901 | 3.44 |
oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor | GO:0016655 | 5.66 |
oxidoreductase activity, acting on NAD(P)H | GO:0016651 | 5.13 |
NADH dehydrogenase (quinone) activity | GO:0050136 | 5.93 |
protein binding | GO:0005515 | 0.46 |
receptor binding | GO:0005102 | 2.43 |
oxidoreductase activity | GO:0016491 | 3.12 |
NADH dehydrogenase activity | GO:0003954 | 5.93 |
binding | GO:0005488 | 0.18 |