Gene table of MTO1 : mitochondrial tRNA translation optimization 1

Gene-disease associations table

Disease ID	Disease name	Source of annotation with MTO1	OMIM link	Number of associated genes	genes
PS609060	COMBINED OXIDATIVE PHOSPHORYLATION DEFICIENCY	ClinVar, OMIM, HUMSAVAR	link to OMIM	29	C12orf65, FARS2, GFM1, TARS2, MTFMT, MTO1, AIFM1, EARS2, NARS2, SFXN4, MRPS22, PNPT1, TSFM, ATP5A1, LYRM4, SLC25A26, MRPS16, MRPL3, TUFM, TRMT5, MRPL44, GTPBP3, VARS2, CARS2, RMND1, ELAC2, AARS2, TXN2, MARS2

Associated genes in ENSEMBL

Associated proteins - SwissProt Accession ID

Associated PDB IDs

Cytogenetic Band

Tandem repeats annotation

Transcription regulation as annotated in TRRUST

Associated KEGG pathways

Associated REACTOME pathways

Associated GO terms for Molecular function

GO term	GO ID	GO IC
coenzyme binding	GO:0050662	4.53
flavin adenine dinucleotide binding	GO:0050660	5.41
organic cyclic compound binding	GO:0097159	1.05
poly(A) RNA binding	GO:0044822	2.69
nucleotide binding	GO:0000166	1.96
small molecule binding	GO:0036094	1.89
catalytic activity	GO:0003824	1.05
cofactor binding	GO:0048037	4.16
binding	GO:0005488	0.18
nucleic acid binding	GO:0003676	1.44
oxidoreductase activity	GO:0016491	3.12
heterocyclic compound binding	GO:1901363	1.06
nucleoside phosphate binding	GO:1901265	1.96
RNA binding	GO:0003723	2.36