Gene table of MYC : v-myc avian myelocytomatosis viral oncogene homolog

Gene-disease associations table

Disease IDDisease nameSource of annotation with MYCOMIM linkNumber of associated genesgenes

Download the gene annotation in CSV format

Annotation of the gene MYC

Associated genes in ENSEMBL
Associated proteins - SwissProt Accession ID
Associated PDB IDs
Cytogenetic Band
Tandem repeats annotation
Transcription regulation as annotated in TRRUST

It is a TF of the genes:

It is regulated by the following TF:

Associated KEGG pathways
Signaling pathways regulating pluripotency of stem cellshsa045505.6
Bladder cancerhsa052197.38
Endometrial cancerhsa052136.81
Colorectal cancerhsa052106.52
MAPK signaling pathwayhsa040104.63
Thyroid cancerhsa052167.48
Jak-STAT signaling pathwayhsa046305.44
Central carbon metabolism in cancerhsa052306.7
Epstein-Barr virus infectionhsa051694.97
HTLV-I infectionhsa051664.59
Wnt signaling pathwayhsa043105.49
Hepatitis Bhsa051615.52
TGF-beta signaling pathwayhsa043506.41
Proteoglycans in cancerhsa052055.02
Cell cyclehsa041105.68
MicroRNAs in cancerhsa052065.38
Pathways in cancerhsa052003.98
Transcriptional misregulation in cancerhsa052025.21
Hippo signaling pathwayhsa043905.37
ErbB signaling pathwayhsa040126.15
Acute myeloid leukemiahsa052216.74
Chronic myeloid leukemiahsa052206.48
Thyroid hormone signaling pathwayhsa049195.82
PI3K-Akt signaling pathwayhsa041514.21
Small cell lung cancerhsa052226.17
Associated REACTOME pathways
Signaling by NOTCHR-HSA-1571186.2
Cell CycleR-HSA-16401703.89
binding of TCF/LEF:CTNNB1 to target gene promotersR-HSA-441136410.18
MAPK family signaling cascadesR-HSA-56830574.89
Generic Transcription PathwayR-HSA-2124363.86
Gene ExpressionR-HSA-741602.72
Cell Cycle, MitoticR-HSA-692784.16
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimerR-HSA-21737937.56
Constitutive Signaling by NOTCH1 HD+PEST Domain MutantsR-HSA-28948627.15
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcriptionR-HSA-21737968.03
Mitotic G1-G1/S phasesR-HSA-4532795.91
Diseases of signal transductionR-HSA-56632024.89
MAPK6/MAPK4 signalingR-HSA-56871286.54
Signaling by TGF-beta Receptor ComplexR-HSA-1708346.81
Signaling by NOTCH1R-HSA-19801436.81
NOTCH1 Intracellular Domain Regulates TranscriptionR-HSA-21229477.43
Signaling by WntR-HSA-1957214.79
formation of the beta-catenin:TCF transactivating complexR-HSA-2017227.18
Cyclin A:Cdk2-associated events at S phase entryR-HSA-696566.94
G1/S TransitionR-HSA-692066.21
Signaling by NOTCH1 in CancerR-HSA-26446037.15
Signaling by NOTCH1 PEST Domain Mutants in CancerR-HSA-26446027.15
Cyclin E associated events during G1/S transition R-HSA-692026.96
Constitutive Signaling by NOTCH1 PEST Domain MutantsR-HSA-26446067.15
S PhaseR-HSA-692426.02
Signaling by NOTCH1 HD+PEST Domain Mutants in CancerR-HSA-28948587.15
TCF dependent signaling in response to WNTR-HSA-2016815.36
Signal TransductionR-HSA-1625821.78
Associated GO terms for Molecular function
RNA polymerase II regulatory region DNA bindingGO:00010123.36
core promoter proximal region DNA bindingGO:00011593.82
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific bindingGO:00010774.31
macromolecular complex bindingGO:00448772.61
nucleic acid binding transcription factor activityGO:00010712.65
nucleic acid bindingGO:00036761.44
DNA bindingGO:00036771.92
E-box bindingGO:00708886.21
heterocyclic compound bindingGO:19013631.06
repressing transcription factor bindingGO:00704915.71
sequence-specific DNA bindingGO:00435652.79
sequence-specific double-stranded DNA bindingGO:19908373.2
core promoter proximal region sequence-specific DNA bindingGO:00009873.83
double-stranded DNA bindingGO:00036903.09
transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific bindingGO:00009823.94
RNA polymerase II transcription factor activity, sequence-specific DNA bindingGO:00009813.29
transcription factor bindingGO:00081343.46
regulatory region nucleic acid bindingGO:00010673.03
protein complex bindingGO:00324033.09
protein dimerization activityGO:00469832.72
transcription regulatory region DNA bindingGO:00442123.03
transcription factor activity, sequence-specific DNA bindingGO:00037002.65
organic cyclic compound bindingGO:00971591.05
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific bindingGO:00012283.98
transcription regulatory region sequence-specific DNA bindingGO:00009763.24
RNA polymerase II regulatory region sequence-specific DNA bindingGO:00009773.37
protein bindingGO:00055150.46
regulatory region DNA bindingGO:00009753.03
RNA polymerase II core promoter proximal region sequence-specific DNA bindingGO:00009783.88