| Disease ID | Disease name | Source of annotation with MYH14 | OMIM link | Number of associated genes | genes |
|---|---|---|---|---|---|
| 614369 | PERIPHERAL NEUROPATHY, MYOPATHY, HOARSENESS, AND HEARING LOSS | ClinVar, OMIM, HUMSAVAR | link to OMIM | 1 | MYH14 |
| PS124900 | DEAFNESS, AUTOSOMAL DOMINANT | ClinVar, OMIM, HUMSAVAR | link to OMIM | 33 | GJB2, DIAPH1, DFNA5, CEACAM16, CRYM, CCDC50, GJB3, KCNQ4, POU4F3, SLC17A8, MYO1A, TBC1D24, MYO7A, COL11A2, MIR96, GJB6, OSBPL2, TMC1, MYO6, P2RX2, EYA4, ACTG1, HOMER2, SIX1, WFS1, KITLG, DIABLO, COCH, TECTA, MYH9, MYH14, TNC, GRHL2 |
Download the gene annotation in CSV format
| KEGG pathway | KEGG ID | KEGG IC |
|---|---|---|
| Tight junction | hsa04530 | 5.53 |
| Salmonella infection | hsa05132 | 6.29 |
| Regulation of actin cytoskeleton | hsa04810 | 4.9 |
| REACTOME pathway | REACTOME ID | REACTOME IC |
|---|---|---|
| RHO GTPases activate CIT | R-HSA-5625900 | 8.98 |
| RHO GTPases activate PKNs | R-HSA-5625740 | 7.1 |
| Sema4D induced cell migration and growth-cone collapse | R-HSA-416572 | 8.4 |
| Sema4D in semaphorin signaling | R-HSA-400685 | 8.23 |
| RHO GTPases Activate ROCKs | R-HSA-5627117 | 8.89 |
| EPHA-mediated growth cone collapse | R-HSA-3928663 | 7.89 |
| Signaling by Rho GTPases | R-HSA-194315 | 4.43 |
| RHO GTPase Effectors | R-HSA-195258 | 4.94 |
| Signal Transduction | R-HSA-162582 | 1.78 |
| Semaphorin interactions | R-HSA-373755 | 6.92 |
| Axon guidance | R-HSA-422475 | 3.93 |
| EPH-Ephrin signaling | R-HSA-2682334 | 6.43 |
| Developmental Biology | R-HSA-1266738 | 3.48 |
| RHO GTPases activate PAKs | R-HSA-5627123 | 8.59 |
| GO term | GO ID | GO IC |
|---|---|---|
| purine ribonucleoside triphosphate binding | GO:0035639 | 2.22 |
| macromolecular complex binding | GO:0044877 | 2.61 |
| binding | GO:0005488 | 0.18 |
| ATPase activity | GO:0016887 | 3.65 |
| heterocyclic compound binding | GO:1901363 | 1.06 |
| purine nucleoside binding | GO:0001883 | 2.22 |
| nucleoside binding | GO:0001882 | 2.21 |
| microfilament motor activity | GO:0000146 | 6.65 |
| ATPase activity, coupled | GO:0042623 | 3.97 |
| nucleotide binding | GO:0000166 | 1.96 |
| actin binding | GO:0003779 | 3.74 |
| nucleoside phosphate binding | GO:1901265 | 1.96 |
| ribonucleoside binding | GO:0032549 | 2.22 |
| protein complex binding | GO:0032403 | 3.09 |
| purine nucleotide binding | GO:0017076 | 2.19 |
| motor activity | GO:0003774 | 4.81 |
| ATP binding | GO:0005524 | 2.43 |
| hydrolase activity | GO:0016787 | 1.9 |
| nucleoside-triphosphatase activity | GO:0017111 | 3.09 |
| actin filament binding | GO:0051015 | 4.93 |
| small molecule binding | GO:0036094 | 1.89 |
| catalytic activity | GO:0003824 | 1.05 |
| actin-dependent ATPase activity | GO:0030898 | 7.17 |
| hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | GO:0016818 | 3.03 |
| adenyl nucleotide binding | GO:0030554 | 2.4 |
| carbohydrate derivative binding | GO:0097367 | 2.03 |
| organic cyclic compound binding | GO:0097159 | 1.05 |
| cytoskeletal protein binding | GO:0008092 | 3.02 |
| hydrolase activity, acting on acid anhydrides | GO:0016817 | 3.03 |
| pyrophosphatase activity | GO:0016462 | 3.04 |
| adenyl ribonucleotide binding | GO:0032559 | 2.41 |
| calmodulin binding | GO:0005516 | 4.55 |
| protein binding | GO:0005515 | 0.46 |
| purine ribonucleotide binding | GO:0032555 | 2.2 |
| purine ribonucleoside binding | GO:0032550 | 2.22 |
| ribonucleotide binding | GO:0032553 | 2.19 |