Gene table of MYLK : myosin light chain kinase

Gene-disease associations table

Disease ID	Disease name	Source of annotation with MYLK	OMIM link	Number of associated genes	genes
PS100070	AORTIC ANEURYSM, FAMILIAL ABDOMINAL	ClinVar	link to OMIM	1	MYLK
PS607086	AORTIC ANEURYSM, FAMILIAL THORACIC	ClinVar, OMIM, HUMSAVAR	link to OMIM	7	TGFBR2, ACTA2, TGFBR1, MYH11, MYLK, PRKG1, MFAP5

Associated genes in ENSEMBL

Associated proteins - SwissProt Accession ID

Associated PDB IDs

Cytogenetic Band

Tandem repeats annotation

Transcription regulation as annotated in TRRUST

Associated KEGG pathways

KEGG pathway	KEGG ID	KEGG IC
Gastric acid secretion	hsa04971	6.48
Platelet activation	hsa04611	5.66
cGMP-PKG signaling pathway	hsa04022	5.32
Calcium signaling pathway	hsa04020	5.22
Focal adhesion	hsa04510	4.92
Vascular smooth muscle contraction	hsa04270	5.74
Oxytocin signaling pathway	hsa04921	5.4
Regulation of actin cytoskeleton	hsa04810	4.9

Associated REACTOME pathways

Associated GO terms for Molecular function

GO term	GO ID	GO IC
purine ribonucleoside triphosphate binding	GO:0035639	2.22
binding	GO:0005488	0.18
nucleotide binding	GO:0000166	1.96
heterocyclic compound binding	GO:1901363	1.06
nucleoside phosphate binding	GO:1901265	1.96
nucleoside binding	GO:0001882	2.21
cation binding	GO:0043169	1.4
ribonucleoside binding	GO:0032549	2.22
ion binding	GO:0043167	1.36
actin binding	GO:0003779	3.74
protein serine/threonine kinase activity	GO:0004674	3.64
transferase activity	GO:0016740	1.95
purine nucleoside binding	GO:0001883	2.22
protein kinase activity	GO:0004672	3.27
purine nucleotide binding	GO:0017076	2.19
metal ion binding	GO:0046872	1.41
ATP binding	GO:0005524	2.43
kinase activity	GO:0016301	2.93
small molecule binding	GO:0036094	1.89
catalytic activity	GO:0003824	1.05
myosin light chain kinase activity	GO:0004687	8.64
cytoskeletal protein binding	GO:0008092	3.02
phosphotransferase activity, alcohol group as acceptor	GO:0016773	3.08
organic cyclic compound binding	GO:0097159	1.05
adenyl nucleotide binding	GO:0030554	2.4
carbohydrate derivative binding	GO:0097367	2.03
adenyl ribonucleotide binding	GO:0032559	2.41
calmodulin binding	GO:0005516	4.55
protein binding	GO:0005515	0.46
transferase activity, transferring phosphorus-containing groups	GO:0016772	2.77
purine ribonucleotide binding	GO:0032555	2.2
purine ribonucleoside binding	GO:0032550	2.22
ribonucleotide binding	GO:0032553	2.19