Disease ID | Disease name | Source of annotation with NCF1 | OMIM link | Number of associated genes | genes |
---|---|---|---|---|---|
PS306400 | GRANULOMATOUS DISEASE, CHRONIC | ClinVar, OMIM, HUMSAVAR | link to OMIM | 5 | CYBA, CYBB, NCF1, NCF2, NCF4 |
Download the gene annotation in CSV format
KEGG pathway | KEGG ID | KEGG IC |
---|---|---|
Leishmaniasis | hsa05140 | 6.32 |
Leukocyte transendothelial migration | hsa04670 | 5.74 |
Phagosome | hsa04145 | 5.27 |
Fc gamma R-mediated phagocytosis | hsa04666 | 6.21 |
Osteoclast differentiation | hsa04380 | 5.64 |
Chemokine signaling pathway | hsa04062 | 5.19 |
REACTOME pathway | REACTOME ID | REACTOME IC |
---|---|---|
Infectious disease | R-HSA-5663205 | 4.47 |
VEGFA-VEGFR2 Pathway | R-HSA-4420097 | 4.7 |
RHO GTPase Effectors | R-HSA-195258 | 4.94 |
RHO GTPases Activate NADPH Oxidases | R-HSA-5668599 | 9.52 |
Signaling by VEGF | R-HSA-194138 | 4.66 |
Antigen processing-Cross presentation | R-HSA-1236975 | 5.88 |
Cross-presentation of particulate exogenous antigens (phagosomes) | R-HSA-1236973 | 9.98 |
Immune System | R-HSA-168256 | 2.37 |
Signaling by Rho GTPases | R-HSA-194315 | 4.43 |
Class I MHC mediated antigen processing & presentation | R-HSA-983169 | 4.65 |
Signal Transduction | R-HSA-162582 | 1.78 |
Latent infection of Homo sapiens with Mycobacterium tuberculosis | R-HSA-1222352 | 7.89 |
Phagosomal maturation (early endosomal stage) | R-HSA-1222556 | 7.89 |
Adaptive Immune System | R-HSA-1280218 | 3.19 |
Disease | R-HSA-1643685 | 3.33 |
GO term | GO ID | GO IC |
---|---|---|
anion binding | GO:0043168 | 4.17 |
electron carrier activity | GO:0009055 | 4.97 |
oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor | GO:0050664 | 6.97 |
phosphatidylinositol binding | GO:0035091 | 4.47 |
phospholipid binding | GO:0005543 | 3.91 |
superoxide-generating NADPH oxidase activity | GO:0016175 | 7.34 |
SH3 domain binding | GO:0017124 | 4.98 |
lipid binding | GO:0008289 | 3.26 |
catalytic activity | GO:0003824 | 1.05 |
phosphatidylinositol-3,4-bisphosphate binding | GO:0043325 | 6.74 |
binding | GO:0005488 | 0.18 |
protein binding | GO:0005515 | 0.46 |
oxidoreductase activity | GO:0016491 | 3.12 |
ion binding | GO:0043167 | 1.36 |
protein domain specific binding | GO:0019904 | 3.32 |
oxidoreductase activity, acting on NAD(P)H | GO:0016651 | 5.13 |