Gene table of NCF2 : neutrophil cytosolic factor 2

Gene-disease associations table

Disease IDDisease nameSource of annotation with NCF2OMIM linkNumber of associated genesgenes
PS306400GRANULOMATOUS DISEASE, CHRONICClinVar, OMIM, HUMSAVAR link to OMIM 5CYBA, CYBB, NCF1, NCF2, NCF4

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Annotation of the gene NCF2

Associated genes in ENSEMBL
Associated proteins - SwissProt Accession ID
Associated PDB IDs
Cytogenetic Band
Tandem repeats annotation
Transcription regulation as annotated in TRRUST

It is regulated by the following TF:

Associated KEGG pathways
KEGG pathwayKEGG IDKEGG IC
Leishmaniasishsa051406.32
Leukocyte transendothelial migrationhsa046705.74
Phagosomehsa041455.27
Osteoclast differentiationhsa043805.64
Associated REACTOME pathways
REACTOME pathwayREACTOME IDREACTOME IC
Infectious diseaseR-HSA-56632054.47
VEGFA-VEGFR2 PathwayR-HSA-44200974.7
RHO GTPase EffectorsR-HSA-1952584.94
RHO GTPases Activate NADPH OxidasesR-HSA-56685999.52
Signaling by VEGFR-HSA-1941384.66
Antigen processing-Cross presentationR-HSA-12369755.88
Cross-presentation of particulate exogenous antigens (phagosomes)R-HSA-12369739.98
Immune SystemR-HSA-1682562.37
Signaling by Rho GTPasesR-HSA-1943154.43
Class I MHC mediated antigen processing & presentationR-HSA-9831694.65
Signal TransductionR-HSA-1625821.78
Latent infection of Homo sapiens with Mycobacterium tuberculosisR-HSA-12223527.89
Phagosomal maturation (early endosomal stage)R-HSA-12225567.89
Adaptive Immune SystemR-HSA-12802183.19
DiseaseR-HSA-16436853.33
Associated GO terms for Molecular function
GO termGO IDGO IC
oxidoreductase activityGO:00164913.12
Rho GTPase bindingGO:00170485.36
protein C-terminus bindingGO:00080224.5
oxidoreductase activity, acting on NAD(P)H, oxygen as acceptorGO:00506646.97
catalytic activityGO:00038241.05
superoxide-generating NADPH oxidase activityGO:00161757.34
Rac GTPase bindingGO:00483656.05
enzyme bindingGO:00198992.27
Ras GTPase bindingGO:00170164.2
small GTPase bindingGO:00312674.13
GTPase bindingGO:00510204.05
bindingGO:00054880.18
protein bindingGO:00055150.46
electron carrier activityGO:00090554.97
oxidoreductase activity, acting on NAD(P)HGO:00166515.13