| Disease ID | Disease name | Source of annotation with NCF4 | OMIM link | Number of associated genes | genes |
|---|---|---|---|---|---|
| PS306400 | GRANULOMATOUS DISEASE, CHRONIC | ClinVar, OMIM, HUMSAVAR | link to OMIM | 5 | CYBA, CYBB, NCF1, NCF2, NCF4 |
Download the gene annotation in CSV format
| KEGG pathway | KEGG ID | KEGG IC |
|---|---|---|
| Leishmaniasis | hsa05140 | 6.32 |
| Leukocyte transendothelial migration | hsa04670 | 5.74 |
| Phagosome | hsa04145 | 5.27 |
| Osteoclast differentiation | hsa04380 | 5.64 |
| REACTOME pathway | REACTOME ID | REACTOME IC |
|---|---|---|
| Infectious disease | R-HSA-5663205 | 4.47 |
| VEGFA-VEGFR2 Pathway | R-HSA-4420097 | 4.7 |
| RHO GTPase Effectors | R-HSA-195258 | 4.94 |
| RHO GTPases Activate NADPH Oxidases | R-HSA-5668599 | 9.52 |
| Signaling by VEGF | R-HSA-194138 | 4.66 |
| Antigen processing-Cross presentation | R-HSA-1236975 | 5.88 |
| Cross-presentation of particulate exogenous antigens (phagosomes) | R-HSA-1236973 | 9.98 |
| Immune System | R-HSA-168256 | 2.37 |
| Signaling by Rho GTPases | R-HSA-194315 | 4.43 |
| Class I MHC mediated antigen processing & presentation | R-HSA-983169 | 4.65 |
| Signal Transduction | R-HSA-162582 | 1.78 |
| Latent infection of Homo sapiens with Mycobacterium tuberculosis | R-HSA-1222352 | 7.89 |
| Phagosomal maturation (early endosomal stage) | R-HSA-1222556 | 7.89 |
| Adaptive Immune System | R-HSA-1280218 | 3.19 |
| Disease | R-HSA-1643685 | 3.33 |
| GO term | GO ID | GO IC |
|---|---|---|
| phosphatidylinositol-3-phosphate binding | GO:0032266 | 6.3 |
| phosphatidylinositol binding | GO:0035091 | 4.47 |
| enzyme regulator activity | GO:0030234 | 2.85 |
| phospholipid binding | GO:0005543 | 3.91 |
| lipid binding | GO:0008289 | 3.26 |
| superoxide-generating NADPH oxidase activator activity | GO:0016176 | 8.13 |
| enzyme activator activity | GO:0008047 | 3.56 |
| protein binding | GO:0005515 | 0.46 |
| phosphatidylinositol phosphate binding | GO:1901981 | 5.05 |
| protein dimerization activity | GO:0046983 | 2.72 |
| molecular function regulator | GO:0098772 | 2.51 |
| binding | GO:0005488 | 0.18 |