Gene table of NEUROD1 : neuronal differentiation 1

Gene-disease associations table

Disease ID	Disease name	Source of annotation with NEUROD1	OMIM link	Number of associated genes	genes
606394	MATURITY-ONSET DIABETES OF THE YOUNG, TYPE 6	ClinVar, OMIM, HUMSAVAR	link to OMIM	1	NEUROD1
125853	DIABETES MELLITUS, NONINSULIN-DEPENDENT	ClinVar, OMIM	link to OMIM	33	SLC2A2, HNF4A, TCF7L2, SLC30A8, GPD2, PAX4, PTPN1, SLC2A4, ABCC8, HMGA1, LIPC, NEUROD1, CDKAL1, WFS1, PPARG, RETN, AKT2, IRS2, IL6, IRS1, GCGR, CAPN10, IGF2BP2, INSR, PDX1, MTNR1B, GCK, HNF1B, HNF1A, MAPK8IP1, ENPP1, PPP1R3A, KCNJ11

Download the gene annotation in CSV format

Annotation of the gene NEUROD1

Associated genes in ENSEMBL

ENSG00000162992

Associated proteins - SwissProt Accession ID

Q13562

Associated PDB IDs

Cytogenetic Band

2q31.3

Tandem repeats annotation

Transcription regulation as annotated in TRRUST

It is a TF of the genes:

It is regulated by the following TF:

NEUROG3

Associated KEGG pathways

KEGG pathway	KEGG ID	KEGG IC
Maturity onset diabetes of the young	hsa04950	8.07

Associated REACTOME pathways

REACTOME pathway	REACTOME ID	REACTOME IC
Regulation of gene expression in endocrine-committed (NEUROG3+) progenitor cells	R-HSA-210746	10.66
Regulation of gene expression in beta cells	R-HSA-210745	8.66
Regulation of beta-cell development	R-HSA-186712	7.98
Developmental Biology	R-HSA-1266738	3.48

Associated GO terms for Molecular function

GO term	GO ID	GO IC
activating transcription factor binding	GO:0033613	5.68
RNA polymerase II regulatory region DNA binding	GO:0001012	3.36
core promoter proximal region DNA binding	GO:0001159	3.82
transcription factor activity, RNA polymerase II transcription factor binding	GO:0001076	4.84
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding	GO:0001077	4.31
macromolecular complex binding	GO:0044877	2.61
binding	GO:0005488	0.18
nucleic acid binding	GO:0003676	1.44
DNA binding	GO:0003677	1.92
transcriptional repressor activity, RNA polymerase II activating transcription factor binding	GO:0098811	5.77
heterocyclic compound binding	GO:1901363	1.06
E-box binding	GO:0070888	6.21
sequence-specific DNA binding	GO:0043565	2.79
transcriptional repressor activity, RNA polymerase II transcription factor binding	GO:0001191	5.28
transcriptional activator activity, RNA polymerase II transcription factor binding	GO:0001190	5.77
transcription coactivator activity	GO:0003713	4.04
transcription cofactor activity	GO:0003712	3.44
transcription factor activity, transcription factor binding	GO:0000989	3.36
transcription factor activity, protein binding	GO:0000988	3.35
core promoter proximal region sequence-specific DNA binding	GO:0000987	3.83
double-stranded DNA binding	GO:0003690	3.09
transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding	GO:0000982	3.94
RNA polymerase II transcription factor activity, sequence-specific DNA binding	GO:0000981	3.29
transcription factor binding	GO:0008134	3.46
regulatory region nucleic acid binding	GO:0001067	3.03
RNA polymerase II transcription cofactor activity	GO:0001104	5.22
RNA polymerase II transcription coactivator activity	GO:0001105	6.15
sequence-specific double-stranded DNA binding	GO:1990837	3.2
RNA polymerase II activating transcription factor binding	GO:0001102	6.13
RNA polymerase II core promoter proximal region sequence-specific DNA binding	GO:0000978	3.88
RNA polymerase II transcription factor binding	GO:0001085	5.08
transcription regulatory region DNA binding	GO:0044212	3.03
protein heterodimerization activity	GO:0046982	3.64
transcription factor activity, sequence-specific DNA binding	GO:0003700	2.65
organic cyclic compound binding	GO:0097159	1.05
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding	GO:0001228	3.98
transcription regulatory region sequence-specific DNA binding	GO:0000976	3.24
RNA polymerase II regulatory region sequence-specific DNA binding	GO:0000977	3.37
protein binding	GO:0005515	0.46
regulatory region DNA binding	GO:0000975	3.03
protein dimerization activity	GO:0046983	2.72
chromatin binding	GO:0003682	3.64
nucleic acid binding transcription factor activity	GO:0001071	2.65