Gene table of NEUROG3 : neurogenin 3

Gene-disease associations table

Disease ID	Disease name	Source of annotation with NEUROG3	OMIM link	Number of associated genes	genes
PS214700	DIARRHEA, CONGENITAL	ClinVar, OMIM, HUMSAVAR	link to OMIM	8	DGAT1, GUCY2C, MYO5B, SLC26A3, SLC9A3, EPCAM, SPINT2, NEUROG3

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Annotation of the gene NEUROG3

Associated genes in ENSEMBL

ENSG00000122859

Associated proteins - SwissProt Accession ID

Q9Y4Z2

Associated PDB IDs

Cytogenetic Band

10q22.1

Tandem repeats annotation

Transcription regulation as annotated in TRRUST

It is a TF of the genes:

It is regulated by the following TF:

FOXO1

Associated KEGG pathways

KEGG pathway	KEGG ID	KEGG IC
Maturity onset diabetes of the young	hsa04950	8.07

Associated REACTOME pathways

REACTOME pathway	REACTOME ID	REACTOME IC
Regulation of gene expression in endocrine-committed (NEUROG3+) progenitor cells	R-HSA-210746	10.66
Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells	R-HSA-210744	10.18
Regulation of beta-cell development	R-HSA-186712	7.98
Developmental Biology	R-HSA-1266738	3.48

Associated GO terms for Molecular function

GO term	GO ID	GO IC
RNA polymerase II regulatory region DNA binding	GO:0001012	3.36
core promoter proximal region DNA binding	GO:0001159	3.82
chromatin DNA binding	GO:0031490	5.37
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding	GO:0001077	4.31
macromolecular complex binding	GO:0044877	2.61
binding	GO:0005488	0.18
nucleic acid binding	GO:0003676	1.44
DNA binding	GO:0003677	1.92
transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding	GO:0001078	5.08
heterocyclic compound binding	GO:1901363	1.06
sequence-specific DNA binding	GO:0043565	2.79
structure-specific DNA binding	GO:0043566	4.98
sequence-specific double-stranded DNA binding	GO:1990837	3.2
transcription coactivator activity	GO:0003713	4.04
transcription cofactor activity	GO:0003712	3.44
transcription factor activity, transcription factor binding	GO:0000989	3.36
transcription factor activity, protein binding	GO:0000988	3.35
core promoter proximal region sequence-specific DNA binding	GO:0000987	3.83
double-stranded DNA binding	GO:0003690	3.09
transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding	GO:0000982	3.94
RNA polymerase II transcription factor activity, sequence-specific DNA binding	GO:0000981	3.29
regulatory region nucleic acid binding	GO:0001067	3.03
core promoter binding	GO:0001047	4.71
RNA polymerase II core promoter proximal region sequence-specific DNA binding	GO:0000978	3.88
transcription regulatory region DNA binding	GO:0044212	3.03
transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding	GO:0001227	4.61
transcription factor activity, sequence-specific DNA binding	GO:0003700	2.65
organic cyclic compound binding	GO:0097159	1.05
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding	GO:0001228	3.98
transcription regulatory region sequence-specific DNA binding	GO:0000976	3.24
RNA polymerase II regulatory region sequence-specific DNA binding	GO:0000977	3.37
protein binding	GO:0005515	0.46
regulatory region DNA binding	GO:0000975	3.03
protein dimerization activity	GO:0046983	2.72
chromatin binding	GO:0003682	3.64
nucleic acid binding transcription factor activity	GO:0001071	2.65