| Disease ID | Disease name | Source of annotation with NF2 | OMIM link | Number of associated genes | genes |
|---|---|---|---|---|---|
| 607174 | MENINGIOMA, FAMILIAL, SUSCEPTIBILITY TO | OMIM | link to OMIM | 6 | PTEN, PDGFB, NF2, MN1, SUFU, SMARCE1 |
| PS162091 | SCHWANNOMATOSIS | OMIM | link to OMIM | 3 | NF2, SMARCB1, LZTR1 |
| 101000 | NEUROFIBROMATOSIS, TYPE II | ClinVar, OMIM, HUMSAVAR | link to OMIM | 1 | NF2 |
Download the gene annotation in CSV format
| KEGG pathway | KEGG ID | KEGG IC |
|---|---|---|
| Hippo signaling pathway | hsa04390 | 5.37 |
| REACTOME pathway | REACTOME ID | REACTOME IC |
|---|---|---|
| RHO GTPase Effectors | R-HSA-195258 | 4.94 |
| Signaling by Rho GTPases | R-HSA-194315 | 4.43 |
| Signal Transduction | R-HSA-162582 | 1.78 |
| RHO GTPases activate PAKs | R-HSA-5627123 | 8.59 |
| GO term | GO ID | GO IC |
|---|---|---|
| integrin binding | GO:0005178 | 5.07 |
| cytoskeletal protein binding | GO:0008092 | 3.02 |
| beta-catenin binding | GO:0008013 | 5.3 |
| actin binding | GO:0003779 | 3.74 |
| macromolecular complex binding | GO:0044877 | 2.61 |
| binding | GO:0005488 | 0.18 |
| protein binding | GO:0005515 | 0.46 |
| protein complex binding | GO:0032403 | 3.09 |
| receptor binding | GO:0005102 | 2.43 |
| cell adhesion molecule binding | GO:0050839 | 4.5 |
| protein domain specific binding | GO:0019904 | 3.32 |