Gene table of NNT : nicotinamide nucleotide transhydrogenase

Gene-disease associations table

Disease ID	Disease name	Source of annotation with NNT	OMIM link	Number of associated genes	genes
PS202200	GLUCOCORTICOID DEFICIENCY	ClinVar, OMIM, HUMSAVAR	link to OMIM	3	MC2R, NNT, MRAP

Associated genes in ENSEMBL

Associated proteins - SwissProt Accession ID

Associated PDB IDs

Cytogenetic Band

Tandem repeats annotation

Transcription regulation as annotated in TRRUST

Associated KEGG pathways

KEGG pathway	KEGG ID	KEGG IC
Nicotinate and nicotinamide metabolism	hsa00760	8.01
Metabolic pathways	hsa01100	2.49

Associated REACTOME pathways

REACTOME pathway	REACTOME ID	REACTOME IC
The citric acid (TCA) cycle and respiratory electron transport	R-HSA-1428517	5.71
Pyruvate metabolism and Citric Acid (TCA) cycle	R-HSA-71406	7.56
Metabolism	R-HSA-1430728	2.34
Citric acid cycle (TCA cycle)	R-HSA-71403	8.73

Associated GO terms for Molecular function

GO term	GO ID	GO IC
NAD binding	GO:0051287	5.77
NAD(P)+ transhydrogenase activity	GO:0008746	9.05
binding	GO:0005488	0.18
heterocyclic compound binding	GO:1901363	1.06
nucleoside phosphate binding	GO:1901265	1.96
oxidoreductase activity	GO:0016491	3.12
coenzyme binding	GO:0050662	4.53
NADP binding	GO:0050661	5.93
transmembrane transporter activity	GO:0022857	2.82
nucleotide binding	GO:0000166	1.96
NAD(P)+ transhydrogenase (B-specific) activity	GO:0003957	9.74
transporter activity	GO:0005215	2.57
cation transmembrane transporter activity	GO:0008324	3.32
NAD(P)+ transhydrogenase (AB-specific) activity	GO:0008750	9.74
small molecule binding	GO:0036094	1.89
catalytic activity	GO:0003824	1.05
cofactor binding	GO:0048037	4.16
substrate-specific transmembrane transporter activity	GO:0022891	2.9
inorganic cation transmembrane transporter activity	GO:0022890	3.49
substrate-specific transporter activity	GO:0022892	2.72
organic cyclic compound binding	GO:0097159	1.05
ion transmembrane transporter activity	GO:0015075	3.04
monovalent inorganic cation transmembrane transporter activity	GO:0015077	3.87
oxidoreductase activity, acting on NAD(P)H	GO:0016651	5.13
oxidoreductase activity, acting on NAD(P)H, NAD(P) as acceptor	GO:0016652	9.05
hydrogen ion transmembrane transporter activity	GO:0015078	5.01