Gene table of NR3C1 : nuclear receptor subfamily 3 group C member 1

Gene-disease associations table

Disease ID	Disease name	Source of annotation with NR3C1	OMIM link	Number of associated genes	genes
615962	GLUCOCORTICOID RESISTANCE, GENERALIZED	ClinVar, OMIM, HUMSAVAR	link to OMIM	1	NR3C1

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Annotation of the gene NR3C1

Associated genes in ENSEMBL

ENSG00000113580

Associated proteins - SwissProt Accession ID

P04150

Associated PDB IDs

Cytogenetic Band

5q31.3

Tandem repeats annotation

Transcription regulation as annotated in TRRUST

It is a TF of the genes:

It is regulated by the following TF:

Associated KEGG pathways

KEGG pathway	KEGG ID	KEGG IC
Neuroactive ligand-receptor interaction	hsa04080	4.58

Associated REACTOME pathways

REACTOME pathway	REACTOME ID	REACTOME IC
Circadian Clock	R-HSA-400253	7.03
Nuclear Receptor transcription pathway	R-HSA-383280	7.31
Generic Transcription Pathway	R-HSA-212436	3.86
BMAL1:CLOCK,NPAS2 activates circadian gene expression	R-HSA-1368108	7.59
Gene Expression	R-HSA-74160	2.72

Associated GO terms for Molecular function

GO term	GO ID	GO IC
signaling receptor activity	GO:0038023	2.49
signal transducer activity	GO:0004871	2.28
RNA polymerase II regulatory region DNA binding	GO:0001012	3.36
core promoter proximal region DNA binding	GO:0001159	3.82
molecular transducer activity	GO:0060089	2.32
transcription factor activity, RNA polymerase II transcription factor binding	GO:0001076	4.84
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding	GO:0001077	4.31
binding	GO:0005488	0.18
nucleic acid binding	GO:0003676	1.44
DNA binding	GO:0003677	1.92
transcription factor activity, ligand-activated RNA polymerase II transcription factor binding	GO:0038049	9.05
heterocyclic compound binding	GO:1901363	1.06
sequence-specific DNA binding	GO:0043565	2.79
sequence-specific double-stranded DNA binding	GO:1990837	3.2
transition metal ion binding	GO:0046914	2.48
zinc ion binding	GO:0008270	2.66
ion binding	GO:0043167	1.36
transcription factor activity, transcription factor binding	GO:0000989	3.36
transcription factor activity, protein binding	GO:0000988	3.35
core promoter proximal region sequence-specific DNA binding	GO:0000987	3.83
double-stranded DNA binding	GO:0003690	3.09
metal ion binding	GO:0046872	1.41
transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding	GO:0000982	3.94
RNA polymerase II transcription factor activity, sequence-specific DNA binding	GO:0000981	3.29
RNA binding	GO:0003723	2.36
cation binding	GO:0043169	1.4
regulatory region nucleic acid binding	GO:0001067	3.03
lipid binding	GO:0008289	3.26
glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity	GO:0038051	9.74
steroid binding	GO:0005496	5.24
steroid hormone binding	GO:1990239	7.95
hormone binding	GO:0042562	5.53
transcription regulatory region DNA binding	GO:0044212	3.03
transcription factor activity, sequence-specific DNA binding	GO:0003700	2.65
organic cyclic compound binding	GO:0097159	1.05
nucleic acid binding transcription factor activity	GO:0001071	2.65
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding	GO:0001228	3.98
steroid hormone receptor activity	GO:0003707	5.66
transcription regulatory region sequence-specific DNA binding	GO:0000976	3.24
RNA polymerase II regulatory region sequence-specific DNA binding	GO:0000977	3.37
protein binding	GO:0005515	0.46
regulatory region DNA binding	GO:0000975	3.03
glucocorticoid receptor activity	GO:0004883	9.74
RNA polymerase II core promoter proximal region sequence-specific DNA binding	GO:0000978	3.88
receptor activity	GO:0004872	2.32