Gene table of NR3C2 : nuclear receptor subfamily 3 group C member 2

Gene-disease associations table

Disease ID	Disease name	Source of annotation with NR3C2	OMIM link	Number of associated genes	genes
177735	PSEUDOHYPOALDOSTERONISM, TYPE I, AUTOSOMAL DOMINANT	ClinVar, OMIM, HUMSAVAR	link to OMIM	1	NR3C2
605115	HYPERTENSION, EARLY-ONSET, AUTOSOMAL DOMINANT, WITH SEVERE EXACERBATION IN PREGNANCY	OMIM, HUMSAVAR	link to OMIM	1	NR3C2

Associated genes in ENSEMBL

Associated proteins - SwissProt Accession ID

Associated PDB IDs

Cytogenetic Band

Tandem repeats annotation

Transcription regulation as annotated in TRRUST

Associated KEGG pathways

KEGG pathway	KEGG ID	KEGG IC
Aldosterone-regulated sodium reabsorption	hsa04960	7.41

Associated REACTOME pathways

REACTOME pathway	REACTOME ID	REACTOME IC
Nuclear Receptor transcription pathway	R-HSA-383280	7.31
Generic Transcription Pathway	R-HSA-212436	3.86
Gene Expression	R-HSA-74160	2.72

Associated GO terms for Molecular function

GO term	GO ID	GO IC
sequence-specific DNA binding	GO:0043565	2.79
metal ion binding	GO:0046872	1.41
nucleic acid binding transcription factor activity	GO:0001071	2.65
nucleic acid binding	GO:0003676	1.44
transition metal ion binding	GO:0046914	2.48
cation binding	GO:0043169	1.4
transcription factor activity, sequence-specific DNA binding	GO:0003700	2.65
organic cyclic compound binding	GO:0097159	1.05
zinc ion binding	GO:0008270	2.66
lipid binding	GO:0008289	3.26
steroid hormone receptor activity	GO:0003707	5.66
signal transducer activity	GO:0004871	2.28
molecular transducer activity	GO:0060089	2.32
receptor activity	GO:0004872	2.32
protein binding	GO:0005515	0.46
DNA binding	GO:0003677	1.92
steroid binding	GO:0005496	5.24
signaling receptor activity	GO:0038023	2.49
ion binding	GO:0043167	1.36
heterocyclic compound binding	GO:1901363	1.06
binding	GO:0005488	0.18